Yina. Li, et.al., Cholesterol modification restricts the spread of Shh gradient in the limb bud., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/16611729

Yina. Li, et.al., Cholesterol modification restricts the spread of Shh gradient in the limb bud., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Shh<tm3(cre)Chg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759540
• Shh<tm2Chg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3628824

class

http://purl.org/net/cito/citesAsAuthority

• Shh<tm3(cre)Chg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759540
• Shh<tm2Chg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3628824

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• preaxial polydactyly_Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0009743I129S1Sv129X1SvJC57BL6CBADisp1tm1PabDisp1tm1PabShhtm2ChgShhTgSox2cre1Amc0Shhtm2ChgDisp1tm1PabTgSox2cre1AmcShh
• neonatal lethality, complete penetrance_Shh<tm2Chg>/Shh<tm2Chg>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJShhtm2ChgShhtm2ChgShhtm2Chg
• abnormal carpal bone morphology_Shh<tm1Chg>/Shh<tm2Chg>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000554I129S1Sv129X1SvJC57BL6CBAShhtm1ChgShhtm2ChgTgSox2cre1Amc0TgSox2cre1AmcShhtm1ChgShhtm2Chg
• polydactyly_Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000562I129S1Sv129X1SvJC57BL6CBAShhtm2ChgShhTgSox2cre1Amc0ShhTgSox2cre1AmcShhtm2Chg
• abnormal tarsal bone morphology_Shh<tm1Chg>/Shh<tm2Chg>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0005104I129S1Sv129X1SvJC57BL6CBAShhtm1ChgShhtm2ChgTgSox2cre1Amc0TgSox2cre1AmcShhtm1ChgShhtm2Chg
• perinatal lethality, complete penetrance_Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJC57BL6CBADisp1tm1PabDisp1tm1PabShhtm2ChgShhTgSox2cre1Amc0Shhtm2ChgDisp1tm1PabTgSox2cre1AmcShh
• abnormal digit morphology_Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002110I129S1Sv129X1SvJC57BL6CBADisp1tm1PabDisp1tm1PabShhtm2ChgShhTgSox2cre1Amc0Shhtm2ChgDisp1tm1PabTgSox2cre1AmcShh
• abnormal digit morphology_Shh<tm1Chg>/Shh<tm2Chg>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002110I129S1Sv129X1SvJC57BL6CBAShhtm1ChgShhtm2ChgTgSox2cre1Amc0TgSox2cre1AmcShhtm1ChgShhtm2Chg