Michiko. Shimoda, et.al., Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance., Journal of immunology (Baltimore, Md. : 1950), 2006, 176

http://rdf.ncbi.nlm.nih.gov/pubmed/16709807

Michiko. Shimoda, et.al., Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance., Journal of immunology (Baltimore, Md. : 1950), 2006, 176

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• H2-Ab1<tm1.1Koni>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5285594

class

http://purl.org/net/cito/citesAsAuthority

• H2-Ab1<tm1.1Koni>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5285594

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased CD4-positive, alpha beta T cell number_Il2<tm1Hor>/Il2<tm1Hor>
  http://metadb.riken.jp/0008074B6129P2Il2tm1HorJIl2tm1HorIl2tm1HorIl2tm1Hor
• decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_Il2<tm1Hor>/Il2<tm1Hor>
  http://metadb.riken.jp/0010169B6129P2Il2tm1HorJIl2tm1HorIl2tm1HorIl2tm1Hor
• abnormal T cell activation_H2-Ab1<tm1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001828I129X1SvJC3HC57BL6C57BL6JH2Ab1tm1KoniH2Ab1tm11KoniTgTekcre12Flv0TgTekcre12FlvH2Ab1tm1KoniH2Ab1tm11Koni
• decreased level of surface class II molecules_H2-Ab1<tm1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0010539I129X1SvJC3HC57BL6C57BL6JH2Ab1tm1KoniH2Ab1tm11KoniTgTekcre12Flv0TgTekcre12FlvH2Ab1tm1KoniH2Ab1tm11Koni
• decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_H2-Ab1<tm1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0010169I129X1SvJC3HC57BL6C57BL6JH2Ab1tm1KoniH2Ab1tm11KoniTgTekcre12Flv0TgTekcre12FlvH2Ab1tm1KoniH2Ab1tm11Koni
• increased splenocyte number_Il2<tm1Hor>/Il2<tm1Hor>
  http://metadb.riken.jp/0009338B6129P2Il2tm1HorJIl2tm1HorIl2tm1HorIl2tm1Hor
• abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology_H2-Ab1<tm1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008397I129X1SvJC3HC57BL6C57BL6JH2Ab1tm1KoniH2Ab1tm11KoniTgTekcre12Flv0TgTekcre12FlvH2Ab1tm1KoniH2Ab1tm11Koni
• increased CD4-positive, alpha beta T cell number_H2-Ab1<tm1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008074I129X1SvJC3HC57BL6C57BL6JH2Ab1tm1KoniH2Ab1tm11KoniTgTekcre12Flv0TgTekcre12FlvH2Ab1tm1KoniH2Ab1tm11Koni
• preweaning lethality, incomplete penetrance_H2-Ab1<tm1.1Koni>/H2-Ab1<tm1.1Koni>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0011110I129X1SvJC3HC57BL6C57BL6JH2Ab1tm11KoniH2Ab1tm11KoniTgTekcre12Flv0H2Ab1tm11KoniTgTekcre12Flv