Sarah L. Hayward, et.al., CD4 T cells play major effector role and CD8 T cells initiating role in spontaneous autoimmune myocarditis of HLA-DQ8 transgenic IAb knockout nonobese diabetic mice., Journal of immunology (Baltimore, Md. : 1950), 2006, 176

http://rdf.ncbi.nlm.nih.gov/pubmed/16751419

Sarah L. Hayward, et.al., CD4 T cells play major effector role and CD8 T cells initiating role in spontaneous autoimmune myocarditis of HLA-DQ8 transgenic IAb knockout nonobese diabetic mice., Journal of immunology (Baltimore, Md. : 1950), 2006, 176

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3590083

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• atrioventricular block_B2m<tm1Unc>/B2m<tm1Unc>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0010519NODCgB2mtm1UncH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllB2mtm1UncB2mtm1UncH2Ab1tm1GruH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllB2mtm1UncH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• prolonged PR interval_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003896NODCgH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• prolonged PR interval_B2m<tm1Unc>/B2m<tm1Unc>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003896NODCgB2mtm1UncH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllB2mtm1UncB2mtm1UncH2Ab1tm1GruH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllB2mtm1UncH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• heart inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0001853NODCgIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruIghmtm1CgnIghmtm1CgnTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• enlarged heart_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0000274NODCgIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruIghmtm1CgnIghmtm1CgnTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• myocarditis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0001856NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom
• abnormal PR interval_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003901NODCgIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruIghmtm1CgnIghmtm1CgnTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllIghmtm1CgnH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• increased autoantibody level_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003725NODCgH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11Ell
• prolonged PR interval_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003896NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom
• increased autoantibody level_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0003725NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom
• abnormal response to transplant_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0005671NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom
• enlarged heart_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0000274NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom
• heart inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell
  http://metadb.riken.jp/0001853NODCgRag1tm1MomH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgCD2CD4HLADQA1HLADQB11EllTgCD2CD4HLADQA1HLADQB11EllH2Ab1tm1GruTgCD2CD4HLADQA1HLADQB11EllRag1tm1Mom

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3590083