Ulf. Klein, et.al., Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination., Nature immunology, 2006, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/16767092

Ulf. Klein, et.al., Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination., Nature immunology, 2006, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Irf4<tm1Rdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664434
• Irf4<tm1.1Rdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3712352

class

http://purl.org/net/cito/citesAsAuthority

• Irf4<tm1Rdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664434
• Irf4<tm1.1Rdf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3712352

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent spleen germinal center_Irf4<tm1.1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0008474I129S1Sv129S4SvJaeC57BL6Irf4tm11RdfIrf4tm11RdfIrf4tm11Rdf
• decreased IgG1 level_Irf4<tm1.1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0008495I129S1Sv129S4SvJaeC57BL6Irf4tm11RdfIrf4tm11RdfIrf4tm11Rdf
• decreased IgG1 level_Ighg1<tm1(cre)Cgn>/Ighg1<+>,Irf4<tm1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0008495I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Ighg1tm1creCgnIghg1Irf4tm1RdfIrf4tm11RdfIghg1Irf4tm11RdfIghg1tm1creCgnIrf4tm1Rdf
• abnormal class switch recombination_Ighg1<tm1(cre)Cgn>/Ighg1<+>,Irf4<tm1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0004816I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Ighg1tm1creCgnIghg1Irf4tm1RdfIrf4tm11RdfIghg1Irf4tm11RdfIghg1tm1creCgnIrf4tm1Rdf
• absent plasma cells_Ighg1<tm1(cre)Cgn>/Ighg1<+>,Irf4<tm1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0008100I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Ighg1tm1creCgnIghg1Irf4tm1RdfIrf4tm11RdfIghg1Irf4tm11RdfIghg1tm1creCgnIrf4tm1Rdf
• decreased B cell proliferation_Irf4<tm1.1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0005093I129S1Sv129S4SvJaeC57BL6Irf4tm11RdfIrf4tm11RdfIrf4tm11Rdf
• abnormal B cell physiology_Irf4<tm1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0002459I129S1Sv129S4SvJaeC57BL6Irf4tm1RdfIrf4tm11RdfIrf4tm1RdfIrf4tm11Rdf
• abnormal B cell differentiation_Irf4<tm1.1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0002144I129S1Sv129S4SvJaeC57BL6Irf4tm11RdfIrf4tm11RdfIrf4tm11Rdf
• abnormal B cell physiology_Irf4<tm1.1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0002459I129S1Sv129S4SvJaeC57BL6Irf4tm11RdfIrf4tm11RdfIrf4tm11Rdf
• abnormal memory B cell morphology_Ighg1<tm1(cre)Cgn>/Ighg1<+>,Irf4<tm1Rdf>/Irf4<tm1.1Rdf>
  http://metadb.riken.jp/0002440I129P2OlaHsd129S1Sv129S4SvJaeSorC57BL6Ighg1tm1creCgnIghg1Irf4tm1RdfIrf4tm11RdfIghg1Irf4tm11RdfIghg1tm1creCgnIrf4tm1Rdf