Xiaoling. Xu, et.al., Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice., The Journal of clinical investigation, 2006, 116

http://rdf.ncbi.nlm.nih.gov/pubmed/16767220

Xiaoling. Xu, et.al., Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice., The Journal of clinical investigation, 2006, 116

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged liver_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000599I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu
• increased hepatocellular carcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0003331I129S4SvJaeFVBNPtentm1HwuPtentm1HwuTgAlb1cre1Dlr0TgAlb1cre1DlrPtentm1Hwu
• bile duct hyperplasia_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0004839I129S4SvJaeFVBNPtentm1HwuPtentm1HwuTgAlb1cre1Dlr0TgAlb1cre1DlrPtentm1Hwu
• abnormal bile duct morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002928I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu
• increased cholangiocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0010315I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu
• increased cholangiocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0010315I129S4SvJaeFVBNPtentm1HwuPtentm1HwuTgAlb1cre1Dlr0TgAlb1cre1DlrPtentm1Hwu
• increased liver weight_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002981I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu
• hepatic steatosis_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002628I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu
• premature death_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002083I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu