Kenji E. Orii, et.al., Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/16777961

Kenji E. Orii, et.al., Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Xrcc2<tm2Pmc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831320
• Xrcc2<tm1Pmc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3654106

class

http://purl.org/net/cito/citesAsAuthority

• Xrcc2<tm2Pmc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831320
• Xrcc2<tm1Pmc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3654106

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased tumor incidence_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002052EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53Lig4tm1IcrfTrp53Trp53tm1Tyj
• increased tumor incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0002020I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• increased sarcoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0002032I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• perinatal lethality, incomplete penetrance_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0011090EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53Lig4tm1IcrfTrp53Trp53tm1Tyj
• increased lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0012431I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• decreased body weight_Trp53<tm1Tyj>/Trp53<+>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0001262I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53Xrcc2tm1PmcXrcc2tm1PmcTrp53tm1TyjTrp53Xrcc2tm1Pmc
• increased skin tumor incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0010300I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• increased medulloblastoma incidence_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0006283EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53tm1TyjLig4tm1IcrfTrp53tm1Tyj
• premature death_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53Lig4tm1IcrfTrp53Trp53tm1Tyj
• decreased body weight_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0001262I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• decreased neuron apoptosis_Atm<tm1Pmc>/Atm<tm1Pmc>,Lig4<tm1Icrf>/Lig4<tm1Icrf>
  http://metadb.riken.jp/0003204EI129P2OlaHsdorI129S1Sv129X1SvJAtmtm1PmcAtmtm1PmcLig4tm1IcrfLig4tm1IcrfAtmtm1PmcLig4tm1Icrf
• increased T cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<+>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0002024I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53Xrcc2tm1PmcXrcc2tm1PmcTrp53tm1TyjTrp53Xrcc2tm1Pmc
• increased medulloblastoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• increased neuron apoptosis_Lig4<tm1Icrf>/Lig4<tm1Icrf>
  http://metadb.riken.jp/0003203EI129P2OlaHsdorI129S1Sv129X1SvJLig4tm1IcrfLig4tm1IcrfLig4tm1Icrf
• embryonic lethality during organogenesis, complete penetrance_Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0011098I129S1SvC57BL6Xrcc2tm1PmcXrcc2tm1PmcXrcc2tm1Pmc
• increased apoptosis_Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0006042I129S1SvC57BL6Xrcc2tm1PmcXrcc2tm1PmcXrcc2tm1Pmc
• decreased neuron apoptosis_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0003204I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• embryonic lethality during organogenesis, complete penetrance_Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>,Atm<tm1Pmc>/Atm<tm1Pmc>
  http://metadb.riken.jp/0011098I129S1SvXrcc2tm1PmcXrcc2tm1PmcAtmtm1PmcAtmtm1PmcAtmtm1PmcXrcc2tm1Pmc
• increased T cell derived lymphoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0002024I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj
• neonatal lethality, complete penetrance_Atm<tm1Pmc>/Atm<tm1Pmc>,Lig4<tm1Icrf>/Lig4<tm1Icrf>
  http://metadb.riken.jp/0011087EI129P2OlaHsdorI129S1Sv129X1SvJAtmtm1PmcAtmtm1PmcLig4tm1IcrfLig4tm1IcrfAtmtm1PmcLig4tm1Icrf
• increased B cell derived lymphoma incidence_Lig4<tm1Icrf>/Lig4<tm1Icrf>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002023EI129P2OlaHsd129S2SvPasorI129S1Sv129S2SvPas129X1SvJLig4tm1IcrfLig4tm1IcrfTrp53tm1TyjTrp53tm1TyjLig4tm1IcrfTrp53tm1Tyj
• perinatal lethality, incomplete penetrance_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm1Pmc>/Xrcc2<tm1Pmc>
  http://metadb.riken.jp/0011090I129S1Sv129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjXrcc2tm1PmcXrcc2tm1PmcXrcc2tm1PmcTrp53tm1Tyj