Yoshiteru. Sasaki, et.al., Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation., Immunity, 2006, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/16782029

Yoshiteru. Sasaki, et.al., Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation., Immunity, 2006, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687199

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687199

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cell proliferation_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000351I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26SorCd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26Sor
• abnormal B cell differentiation_Ikbkg<tm1.1Mpa>/Ikbkg<tm1.1Mpa>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0002144IBALBcC57BL6Ikbkgtm11MpaIkbkgtm11MpaCd79atm1creRethCd79aCd79atm1creRethCd79aIkbkgtm11Mpa
• abnormal B cell physiology_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002459I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26SorCd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26Sor
• increased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005014I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26SorCd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26Sor
• decreased B cell number_Ikbkg<tm1.1Mpa>/Ikbkg<tm1.1Mpa>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0005017IBALBcC57BL6Ikbkgtm11MpaIkbkgtm11MpaCd79atm1creRethCd79aCd79atm1creRethCd79aIkbkgtm11Mpa
• abnormal enzyme/coenzyme activity_Tnfrsf13c<tm1Mass>/Tnfrsf13c<tm1Mass>,Tg(BCL2)22Wehi/0
  http://metadb.riken.jp/0005584IC57BL6SJLTnfrsf13ctm1MassTnfrsf13ctm1MassTgBCL222Wehi0Tnfrsf13ctm1MassTgBCL222Wehi
他3件を見る
• decreased mature B cell number_Ikbkg<tm1.1Mpa>/Ikbkg<tm1.1Mpa>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0008211IBALBcC57BL6Ikbkgtm11MpaIkbkgtm11MpaCd79atm1creRethCd79aCd79atm1creRethCd79aIkbkgtm11Mpa
• decreased B cell apoptosis_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008783I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26SorCd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26Sor
• abnormal splenic cell ratio_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008826I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26SorCd19tm1creCgnCd19GtROSA26Sortm4IkbkbRskyGtROSA26Sor