Kendra K. Bence, et.al., Neuronal PTP1B regulates body weight, adiposity and leptin action., Nature medicine, 2006, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/16845389

Kendra K. Bence, et.al., Neuronal PTP1B regulates body weight, adiposity and leptin action., Nature medicine, 2006, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptpn1<tm2Bbk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3663370

class

http://purl.org/net/cito/citesAsAuthority

• Ptpn1<tm2Bbk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3663370

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Ptpn1<tm2Bbk>/Ptpn1<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1TgNescre1Kln0Ptpn1tm2BbkTgNescre1KlnPtpn1
• decreased circulating insulin level_Ptpn1<tm2Bbk>/Ptpn1<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002727I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1TgNescre1Kln0Ptpn1tm2BbkTgNescre1KlnPtpn1
• abnormal motor capabilities/coordination/movement_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002066I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased circulating glucose level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005560I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• abnormal fat pad morphology_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005334I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• increased adiponectin level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004892I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• improved glucose tolerance_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased respiratory quotient_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0010379I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• abnormal food intake_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005449I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased body weight_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• increased insulin sensitivity_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002891I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased circulating glucose level_Ptpn1<tm2Bbk>/Ptpn1<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005560I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1TgNescre1Kln0Ptpn1tm2BbkTgNescre1KlnPtpn1
• decreased food intake_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011940I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• abnormal hormone level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003953I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased bone mineral density_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000063I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• increased circulating leptin level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005669I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased triglyceride level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005318I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• increased oxygen consumption_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005289I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln
• decreased circulating insulin level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002727I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln