Shao H. Yang, et.al., A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation., The Journal of clinical investigation, 2006, 116

http://rdf.ncbi.nlm.nih.gov/pubmed/16862216

Shao H. Yang, et.al., A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation., The Journal of clinical investigation, 2006, 116

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal bone structure_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0003795I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• abnormal skeleton morphology_Lmna<tm1Lgf>/Lmna<tm1Stw>
  http://metadb.riken.jp/0005508I129P2OlaHsd129S1SvC57BL6Lmnatm1LgfLmnatm1StwLmnatm1StwLmnatm1Lgf
• decreased total body fat amount_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0010025I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• premature death_Lmna<tm1Lgf>/Lmna<tm1Stw>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S1SvC57BL6Lmnatm1LgfLmnatm1StwLmnatm1StwLmnatm1Lgf
• abnormal rib morphology_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0000150I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• kyphosis_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• abnormal cranial suture morphology_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0002835I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• weight loss_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0001263I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• abnormal bone mineralization_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0002896I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• decreased abdominal adipose tissue amount_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0008853I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• decreased subcutaneous adipose tissue amount_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0008844I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• premature death_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• decreased bone mineralization_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0020137I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal zygomatic arch morphology_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0004469I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• micrognathia_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0002639I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal cranial suture morphology_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0002835I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal cranium morphology_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0000438I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• micrognathia_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0002639I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna
• premature death_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal skeleton morphology_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0005508I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• abnormal cell nucleus morphology_Lmna<tm1Lgf>/Lmna<tm1Lgf>
  http://metadb.riken.jp/0003111I129P2OlaHsdC57BL6Lmnatm1LgfLmnatm1LgfLmnatm1Lgf
• rib fractures_Lmna<tm1Lgf>/Lmna<+>
  http://metadb.riken.jp/0004675I129P2OlaHsdC57BL6Lmnatm1LgfLmnaLmnatm1LgfLmna