Changwon. Park, et.al., Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation., Development (Cambridge, England), 2006, 133

http://rdf.ncbi.nlm.nih.gov/pubmed/16887829

Changwon. Park, et.al., Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation., Development (Cambridge, England), 2006, 133

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal vascular branching morphogenesis_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003227I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• pericardial effusion_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0005312I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• absent atrioventricular cushions_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0000298I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• abnormal vein morphology_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0002725I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• small heart_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0002188I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• embryonic lethality during organogenesis, complete penetrance_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0011098I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• pale yolk sac_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001722I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• hemorrhage_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001914I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• abnormal vitelline vasculature morphology_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003229I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• decreased embryo size_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001698I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• absent atrioventricular cushions_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0000298I129S1Sv129S6SvEvTacSmad4tm21CxdSmad4tm21CxdKdrtm1creSatoKdrSmad4tm21CxdKdrtm1creSatoKdr
• embryonic lethality during organogenesis, complete penetrance_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0011098I129S1Sv129S6SvEvTacSmad4tm21CxdSmad4tm21CxdKdrtm1creSatoKdrSmad4tm21CxdKdrtm1creSatoKdr
• abnormal visceral yolk sac morphology_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001718I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• abnormal vascular development_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0000259I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• abnormal vitelline vasculature morphology_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003229I129S1Sv129S6SvEvTacSmad4tm21CxdSmad4tm21CxdKdrtm1creSatoKdrSmad4tm21CxdKdrtm1creSatoKdr
• internal hemorrhage_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001634I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• embryonic growth arrest_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0001730I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• abnormal embryonic hematopoiesis_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003396I129S1Sv129S6SvEvTacSmad4tm21CxdSmad4tm21CxdKdrtm1creSatoKdrSmad4tm21CxdKdrtm1creSatoKdr
• abnormal trabecula carnea morphology_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0004067I129S1Sv129S6SvEvTacSmad4tm21CxdSmad4tm21CxdKdrtm1creSatoKdrSmad4tm21CxdKdrtm1creSatoKdr
• pallor_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003717I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr
• vascular smooth muscle hypoplasia_Bmpr1a<tm2.1Bhr>/Bmpr1a<tm2.1Bhr>,Kdr<tm1(cre)Sato>/Kdr<+>
  http://metadb.riken.jp/0003814I129S1Sv129S7SvEvBrdBmpr1atm21BhrBmpr1atm21BhrKdrtm1creSatoKdrBmpr1atm21BhrKdrtm1creSatoKdr

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD11012
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11012