Kristina. Bry, et.al., IL-1beta disrupts postnatal lung morphogenesis in the mouse., American journal of respiratory cell and molecular biology, 2007, 36

http://rdf.ncbi.nlm.nih.gov/pubmed/16888287

Kristina. Bry, et.al., IL-1beta disrupts postnatal lung morphogenesis in the mouse., American journal of respiratory cell and molecular biology, 2007, 36

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased respiratory mucosa goblet cell number_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0010861I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• decreased body weight_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0001262I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• lung inflammation_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0001861I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• postnatal growth retardation_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0001732I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• thick pulmonary interalveolar septum_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0001179I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal pulmonary alveolus wall morphology_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0010903I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• respiratory failure_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0001953I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal lung epithelium morphology_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0006382I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal pulmonary elastic fiber morphology_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0003209I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal lung vasculature morphology_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0004007I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal lung alveolus development_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0010995I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• postnatal lethality, incomplete penetrance_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0011086I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw
• abnormal chemokine level_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-IL1B)KBry/0
  http://metadb.riken.jp/0008721I129C57BL6TgScgb1a1rtTA1Jaw0TgtetOIL1BKBry0TgtetOIL1BKBryTgScgb1a1rtTA1Jaw