Eric C C. Cheung, et.al., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis., The EMBO journal, 2006, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/16917506

Eric C C. Cheung, et.al., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis., The EMBO journal, 2006, 25

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal mitochondrial physiology_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>,Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006036I129P2OlaHsd129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmApaf1GtIRESBetageoXIX18PgrFoxg1Aifm1tm2Pngr
• decreased neuron apoptosis_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003204I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• abnormal enzyme/coenzyme level_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0005319I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• thickened cerebral cortex_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>,Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000789I129P2OlaHsd129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmApaf1GtIRESBetageoXIX18PgrFoxg1Aifm1tm2Pngr
• increased neuron apoptosis_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0003203I129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• increased neuron apoptosis_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>,Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003203I129P2OlaHsd129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmApaf1GtIRESBetageoXIX18PgrFoxg1Aifm1tm2Pngr
• thin cerebral cortex_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006254I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• decreased mitochondrial fission_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006039I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• decreased neuron apoptosis_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>,Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003204I129P2OlaHsd129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmApaf1GtIRESBetageoXIX18PgrFoxg1Aifm1tm2Pngr
• abnormal mitochondrial physiology_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006036I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• decreased neuron apoptosis_Apaf1<Gt(IRESBetageo)XIX18Pgr>/Apaf1<Gt(IRESBetageo)XIX18Pgr>
  http://metadb.riken.jp/0003204I129S1Sv129X1SvJApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18PgrApaf1GtIRESBetageoXIX18Pgr
• abnormal mitochondrion morphology_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006035I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• increased neuron apoptosis_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003203I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1
• lethality throughout fetal growth and development, incomplete penetrance_Aifm1<tm2Pngr>/Y,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0011109I129P2OlaHsdAifm1tm2PngrYFoxg1tm1creSkmFoxg1Foxg1tm1creSkmAifm1tm2PngrFoxg1