Shintaro. Sato, et.al., TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells., International immunology, 2006, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/16940043

Shintaro. Sato, et.al., TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells., International immunology, 2006, 18

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0005018I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• weight loss_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0001263I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• decreased CD4-positive, alpha beta T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008075I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• enlarged lymph nodes_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000702I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• intestinal ulcer_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000512I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• abnormal T cell activation_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0001828I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• abnormal colon morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000495I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• chronic diarrhea_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0001665I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• decreased CD8-positive, alpha-beta T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008079I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• abnormal spleen morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000689I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• abnormal intestine morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000477I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• decreased single-positive T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008083I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• decreased T cell proliferation_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0005095I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• enlarged spleen_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000691I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• increased memory T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008049I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• abnormal intestinal goblet cell morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0003449I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• absent regulatory T cells_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0004975I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• colitis_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0002816I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• spleen hyperplasia_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000693I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki
• rectal prolapse_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000493I129P2OlaHsdMap3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0TgLckcre1JtakMap3k7tm1Aki