R A. Jones, et.al., Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation., Oncogene, 2007, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/16953219

R A. Jones, et.al., Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation., Oncogene, 2007, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-IGF1R)1Ramo
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432255

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-IGF1R)1Ramo
  http://metadb.riken.jp/db/mgi_rdf/MGI:5432255

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal branching of the mammary ductal tree_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0000662IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo
• abnormal mammary gland development_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0000628IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo
• abnormal mammary gland epithelium morphology_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0009504IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo
• mammary gland hyperplasia_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0000630IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo
• increased mammary gland tumor incidence_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0010299IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo
• increased mammary adenocarcinoma incidence_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-IGF1R)1Ramo/0
  http://metadb.riken.jp/0001883IFVBTgMMTVrtTA1Lach0TgtetOIGF1R1Ramo0TgMMTVrtTA1LachTgtetOIGF1R1Ramo