Abdallah. Souabni, et.al., Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus., Blood, 2007, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/16968900

Abdallah. Souabni, et.al., Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus., Blood, 2007, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3699130

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-positive T cell number_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0005092B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• premature death_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0002083B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal salivary gland morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000613B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• decreased double-positive T cell number_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0005092B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• decreased B cell number_Igh<tm1(PAX5)Mbu>/Igh<+>,Pax5<tm1Mbu>/Pax5<tm1Mbu>
  http://metadb.riken.jp/0005017I129P2OlaHsd129S2SvPasC57BL6CBAIghtm1PAX5MbuIghPax5tm1MbuPax5tm1MbuIghPax5tm1MbuIghtm1PAX5Mbu
• thymus hypoplasia_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0001823B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• thymus hypoplasia_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0001823B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• increased lymphoma incidence_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0012431B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal thymus morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000703B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal spleen morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000689B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal kidney morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0002135B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal spleen morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000689B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• thymus hypoplasia_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0001823I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• abnormal heart morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000266B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• decreased double-positive T cell number_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• premature death_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• decreased double-negative T cell number_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0005089B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• enlarged spleen_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000691B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• increased T cell derived lymphoma incidence_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0002024I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• abnormal lymph node morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0002339B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• increased pro-B cell number_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0008186B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• enlarged thymus_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000709B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• enlarged lymph nodes_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000702B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal lung morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0001175B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• enlarged thymus_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0000709I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• enlarged spleen_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• abnormal lymph node morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0002339B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal liver morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000598B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• enlarged spleen_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000691B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• increased T cell derived lymphoma incidence_Ikzf1<tm1(Pax5)Mbu>/Ikzf1<+>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0002024I129P2OlaHsdC57BL6Ikzf1tm1Pax5MbuIkzf1TgLckcre1Cwi0TgLckcre1CwiIkzf1tm1Pax5MbuIkzf1
• abnormal B cell differentiation_Igh<tm1(PAX5)Mbu>/Igh<+>,Pax5<tm1Mbu>/Pax5<tm1Mbu>
  http://metadb.riken.jp/0002144I129P2OlaHsd129S2SvPasC57BL6CBAIghtm1PAX5MbuIghPax5tm1MbuPax5tm1MbuIghPax5tm1MbuIghtm1PAX5Mbu
• enlarged thymus_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000709B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• increased lymphoma incidence_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0012431I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• increased pro-B cell number_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0008186B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• enlarged lymph nodes_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000702B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal T cell differentiation_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0002145B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal salivary gland morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000613B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• enlarged lymph nodes_Ikzf1<tm1.1(Pax5)Mbu>/Ikzf1<+>
  http://metadb.riken.jp/0000702I129P2OlaHsdC57BL6Ikzf1tm11Pax5MbuIkzf1Ikzf1Ikzf1tm11Pax5Mbu
• abnormal kidney morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0002135B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal thymus morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000703B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• premature death_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0002083B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• decreased double-negative T cell number_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0005089B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal lung morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0001175B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• abnormal T cell differentiation_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0002145B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal heart morphology_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0000266B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• abnormal liver morphology_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0000598B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• increased lymphoma incidence_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0012431B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh
• increased T cell derived lymphoma incidence_Igh<tm1(PAX5)Mbu>/Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/0002024B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5MbuIghtm1PAX5Mbu
• increased T cell derived lymphoma incidence_Igh<tm1(PAX5)Mbu>/Igh<+>
  http://metadb.riken.jp/0002024B6CgIghtm1PAX5MbuIghtm1PAX5MbuIghIghtm1PAX5MbuIgh

class

http://purl.org/net/cito/citesAsAuthority

• Igh<tm1(PAX5)Mbu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3699130