Sarah L. Gray, et.al., Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice., Diabetes, 2006, 55

http://rdf.ncbi.nlm.nih.gov/pubmed/17003330

Sarah L. Gray, et.al., Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice., Diabetes, 2006, 55

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pparg<tm1Avp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3694813

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating triglyceride level_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0001552I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• increased liver weight_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002981I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• hepatic steatosis_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002628I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• hepatic steatosis_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002628I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• abnormal gonadal fat pad morphology_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0005335I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• abnormal lipid homeostasis_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002118I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• abnormal white adipose tissue amount_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0001781I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• abnormal adipose tissue distribution_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0000013I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• abnormal glucose homeostasis_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002078I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• decreased body weight_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0001262I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• decreased fat cell size_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0009269I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• insulin resistance_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0005331I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• increased liver weight_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002981I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• increased circulating triglyceride level_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0001552I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• abnormal skeletal muscle morphology_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0000759I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• decreased body fat mass_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0014143I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• abnormal triglyceride level_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0000187I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• abnormal fat cell morphology_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0009115I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• increased circulating insulin level_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0002079I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• preweaning lethality, complete penetrance_Pparg<tm1Avp>/Pparg<tm1Avp>
  http://metadb.riken.jp/0011100I129S2SvPasC57BL6Ppargtm1AvpPpargtm1AvpPpargtm1Avp
• decreased adiponectin level_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0004893I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• increased circulating glucose level_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0005559I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp
• decreased adiponectin level_Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0004893I129S2SvPasC57BL6Ppargtm1AvpPpargPpargtm1AvpPparg
• polyphagia_Lep<ob>/Lep<ob>,Pparg<tm1Avp>/Pparg<+>
  http://metadb.riken.jp/0001433I129S2SvPasC57BL6LepobLepobPpargtm1AvpPpargPpargLepobPpargtm1Avp

class

http://purl.org/net/cito/citesAsAuthority

• Pparg<tm1Avp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3694813