Graham B. Sinclair, et.al., Generation of a conditional knockout of murine glucocerebrosidase: utility for the study of Gaucher disease., Molecular genetics and metabolism, 2007, 90

http://rdf.ncbi.nlm.nih.gov/pubmed/17079175

Graham B. Sinclair, et.al., Generation of a conditional knockout of murine glucocerebrosidase: utility for the study of Gaucher disease., Molecular genetics and metabolism, 2007, 90

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gba<tm1.1Clk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698019
• Gba<tm1Clk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698018

class

http://purl.org/net/cito/citesAsAuthority

• Gba<tm1.1Clk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698019
• Gba<tm1Clk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698018

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow morphology_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002397I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• increased spleen weight_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0004952I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• abnormal macrophage morphology_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0002446I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• neonatal lethality, complete penetrance_Gba<tm1.1Clk>/Gba<tm1.1Clk>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJC57BL6JGbatm11ClkGbatm11ClkGbatm11Clk
• abnormal enzyme/coenzyme activity_Gba<tm1Clk>/Gba<tm1.1Clk>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0005584I129P2OlaHsd129S1Sv129X1SvJC57BL6JGbatm1ClkGbatm11ClkLyz2tm1creIfoLyz2Gbatm1ClkGbatm11ClkLyz2Lyz2tm1creIfo
• abnormal enzyme/coenzyme activity_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0005584I129S1Sv129X1SvJC57BL6JFVBNGbatm1ClkGbatm11ClkTgEIIacreC5379Lmgd0Gbatm1ClkTgEIIacreC5379LmgdGbatm11Clk
• wrinkled skin_Gba<tm1.1Clk>/Gba<tm1.1Clk>
  http://metadb.riken.jp/0001211I129S1Sv129X1SvJC57BL6JGbatm11ClkGbatm11ClkGbatm11Clk
• reddish skin_Gba<tm1.1Clk>/Gba<tm1.1Clk>
  http://metadb.riken.jp/0001190I129S1Sv129X1SvJC57BL6JGbatm11ClkGbatm11ClkGbatm11Clk
• abnormal enzyme/coenzyme activity_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0005584I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• abnormal liver morphology_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000598I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• abnormal spleen morphology_Gba<tm1Clk>/Gba<tm1.1Clk>,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0000689I129S1Sv129X1SvJC3HC57BL6JGbatm1ClkGbatm11ClkTgTekcre12Flv0Gbatm11ClkGbatm1ClkTgTekcre12Flv
• aphagia_Gba<tm1.1Clk>/Gba<tm1.1Clk>
  http://metadb.riken.jp/0001438I129S1Sv129X1SvJC57BL6JGbatm11ClkGbatm11ClkGbatm11Clk