Minghua. Zhu, et.al., Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB., Immunity, 2006, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/17081783

Minghua. Zhu, et.al., Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB., Immunity, 2006, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lat2<tm2Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693652

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged spleen_Lat<tm1.1Lov>/Lat<tm1.1Lov>,Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLat2tm1WzLat2tm1WzLattm11LovLat2tm1Wz
• increased anti-double stranded DNA antibody level_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0004762B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• increased autoantibody level_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0003725B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• enlarged spleen_Lat<tm1.1Lov>/Lat<tm1.1Lov>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLattm11Lov
• increased activated T cell number_Lat2<tm2Wz>/Lat2<tm2Wz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0001829IC57BL6Lat2tm2WzLat2tm2WzTgLckcre548Jxm0Lat2tm2WzTgLckcre548Jxm
• spleen hyperplasia_Lat<tm1.1Lov>/Lat<tm1.1Lov>
  http://metadb.riken.jp/0000693I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLattm11Lov
• abnormal CD4-positive, alpha beta T cell morphology_Lat<tm1.1Lov>/Lat<tm1.1Lov>,Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0002432I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLat2tm1WzLat2tm1WzLattm11LovLat2tm1Wz
• abnormal CD4-positive, alpha-beta T cell physiology_Lat2<tm2Wz>/Lat2<tm2Wz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005463IC57BL6Lat2tm2WzLat2tm2WzTgLckcre548Jxm0Lat2tm2WzTgLckcre548Jxm
• abnormal CD8-positive, alpha-beta T cell physiology_Tg(CD2-LAT2)1Wz/0
  http://metadb.riken.jp/0004392NSTgCD2LAT21Wz0TgCD2LAT21Wz
• increased T cell proliferation_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0005348B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• spleen hyperplasia_Lat<tm1.1Lov>/Lat<tm1.1Lov>,Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0000693I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLat2tm1WzLat2tm1WzLattm11LovLat2tm1Wz
• enlarged lymph nodes_Lat<tm1.1Lov>/Lat<tm1.1Lov>
  http://metadb.riken.jp/0000702I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLattm11Lov
• spleen hyperplasia_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0000693B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• abnormal CD8-positive, alpha-beta T cell physiology_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0004392B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• enlarged lymph nodes_Lat<tm1.1Lov>/Lat<tm1.1Lov>,Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0000702I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLat2tm1WzLat2tm1WzLattm11LovLat2tm1Wz
• abnormal T cell physiology_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0002444B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• abnormal cytokine secretion_Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0003009B6CgLat2tm1WzLat2tm1WzLat2tm1WzLat2tm1Wz
• abnormal CD4-positive, alpha beta T cell morphology_Lat<tm1.1Lov>/Lat<tm1.1Lov>
  http://metadb.riken.jp/0002432I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLattm11Lov
• enlarged spleen_Lat2<tm2Wz>/Lat2<tm2Wz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0000691IC57BL6Lat2tm2WzLat2tm2WzTgLckcre548Jxm0Lat2tm2WzTgLckcre548Jxm
• increased anti-double stranded DNA antibody level_Lat<tm1.1Lov>/Lat<tm1.1Lov>,Lat2<tm1Wz>/Lat2<tm1Wz>
  http://metadb.riken.jp/0004762I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLat2tm1WzLat2tm1WzLattm11LovLat2tm1Wz
• increased anti-double stranded DNA antibody level_Lat2<tm2Wz>/Lat2<tm2Wz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0004762IC57BL6Lat2tm2WzLat2tm2WzTgLckcre548Jxm0Lat2tm2WzTgLckcre548Jxm
• increased anti-double stranded DNA antibody level_Lat<tm1.1Lov>/Lat<tm1.1Lov>
  http://metadb.riken.jp/0004762I129S1Sv129X1SvJC57BL6Lattm11LovLattm11LovLattm11Lov

class

http://purl.org/net/cito/citesAsAuthority

• Lat2<tm2Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3693652