Ying. Yu, et.al., Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality., The Journal of biological chemistry, 2007, 282

http://rdf.ncbi.nlm.nih.gov/pubmed/17110378

Ying. Yu, et.al., Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality., The Journal of biological chemistry, 2007, 282

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptgs2<tm2(Ptgs1)Fun>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3701117
• Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3699107

class

http://purl.org/net/cito/citesAsAuthority

• Ptgs2<tm2(Ptgs1)Fun>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3701117
• Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3699107

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased vascular permeability_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0003071I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• peritoneal inflammation_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0003303I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• cortical renal glomerulopathies_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0000523I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• decreased litter size_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0001935I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• reduced female fertility_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0001923I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• preweaning lethality, incomplete penetrance_Ptgs2<tm2(Ptgs1)Fun>/Ptgs2<tm2(Ptgs1)Fun>
  http://metadb.riken.jp/0011110I129S1Sv129X1SvJC57BL6Ptgs2tm2Ptgs1FunPtgs2tm2Ptgs1FunPtgs2tm2Ptgs1Fun
• abnormal macrophage physiology_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0002451I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• decreased litter size_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0001935I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• abnormal renal glomerulus morphology_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0005325I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed
• kidney inflammation_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0001859I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• increased blood urea nitrogen level_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0005565I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• abnormal macrophage physiology_Ptgs2<tm2(Ptgs1)Fun>/Ptgs2<tm2(Ptgs1)Fun>
  http://metadb.riken.jp/0002451I129S1Sv129X1SvJC57BL6Ptgs2tm2Ptgs1FunPtgs2tm2Ptgs1FunPtgs2tm2Ptgs1Fun
• prenatal lethality_Ptgs1<tm1Fun>/Ptgs1<tm1Fun>,Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0002080I129S1Sv129S6SvEvTac129X1SvJC57BL6FVBPtgs1tm1FunPtgs1tm1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs1tm1Fun
• decreased urine prostaglandin level_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0011564I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• peritoneal inflammation_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0003303I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• abnormal fertility/fecundity_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0002161I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• decreased vascular permeability_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0003071I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• abnormal renal glomerulus morphology_Ptgs2<tm2.1(Ptgs1)Fun>/Ptgs2<tm2.1(Ptgs1)Fun>
  http://metadb.riken.jp/0005325I129S1Sv129X1SvJC57BL6FVBPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1FunPtgs2tm21Ptgs1Fun
• increased blood urea nitrogen level_Ptgs2<tm1Jed>/Ptgs2<tm1Jed>
  http://metadb.riken.jp/0005565I129S7SvEvBrdC57BL6Ptgs2tm1JedPtgs2tm1JedPtgs2tm1Jed