Tianzhong. Yang, et.al., Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse., Anesthesiology, 2006, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/17122579

Tianzhong. Yang, et.al., Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse., Anesthesiology, 2006, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ryr1<tm2.1Alle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4887389

class

http://purl.org/net/cito/citesAsAuthority

• Ryr1<tm2.1Alle>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4887389

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal calcium ion homeostasis_Ryr1<tm2.1Alle>/Ryr1<tm2.1Alle>
  http://metadb.riken.jp/0004231I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1tm21AlleRyr1tm21Alle
• lethality throughout fetal growth and development, complete penetrance_Ryr1<tm2.1Alle>/Ryr1<tm2.1Alle>
  http://metadb.riken.jp/0011099I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1tm21AlleRyr1tm21Alle
• abnormal calcium ion homeostasis_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0004231I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle
• acidemia_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0003030I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle
• susceptible to malignant hyperthermia_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0020214I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle
• increased pulmonary respiratory rate_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0005573I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle
• increased sensitivity to xenobiotic induced morbidity/mortality_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0009766I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle
• hypercapnia_Ryr1<tm2.1Alle>/Ryr1<+>
  http://metadb.riken.jp/0002318I129S1Sv129X1SvJC57BL6Ryr1tm21AlleRyr1Ryr1Ryr1tm21Alle