Yong. Cang, et.al., Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells., Cell, 2006, 127

http://rdf.ncbi.nlm.nih.gov/pubmed/17129780

Yong. Cang, et.al., Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells., Cell, 2006, 127

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ddb1<tm1Spg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698413
• Ddb1<tm1.1Spg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698414

class

http://purl.org/net/cito/citesAsAuthority

• Ddb1<tm1Spg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698413
• Ddb1<tm1.1Spg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698414

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron apoptosis_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003202I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal lens epithelium morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003237I129P2OlaHsd129S2SvPasC57BL6SJLDdb1tm1SpgDdb1tm1SpgTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0TgNescre1KlnDdb1tm1SpgTrp53tm1Tyj
• abnormal nervous system physiology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003633I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• increased lens epithelium apoptosis_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008794I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• intracranial hemorrhage_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001915I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal lens morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001303I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal blood vessel morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001614I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• embryonic lethality during organogenesis, complete penetrance_Ddb1<tm1.1Spg>/Ddb1<tm1.1Spg>
  http://metadb.riken.jp/0011098I129P2OlaHsdDdb1tm11SpgDdb1tm11SpgDdb1tm11Spg
• intracerebral hemorrhage_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001916I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• neonatal lethality, complete penetrance_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011087I129P2OlaHsd129S2SvPasC57BL6SJLDdb1tm1SpgDdb1tm1SpgTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0TgNescre1KlnDdb1tm1SpgTrp53tm1Tyj
• cataract_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001304I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal fourth ventricle morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000828I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• thin cerebral cortex_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006254I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• cerebellum hemorrhage_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006052I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal cerebellum external granule cell layer morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000872I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• decreased brain size_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000774I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal olfactory bulb morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000819I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal cerebral aqueduct morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005537I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal cerebral cortex morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000788I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• enlarged lateral ventricles_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008535I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• small cerebellum_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal lateral ventricle morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000823I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln
• abnormal brain morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002152I129P2OlaHsd129S2SvPasC57BL6SJLDdb1tm1SpgDdb1tm1SpgTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0TgNescre1KlnDdb1tm1SpgTrp53tm1Tyj
• neonatal lethality, complete penetrance_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011087I129P2OlaHsdC57BL6SJLDdb1tm1SpgDdb1tm1SpgTgNescre1Kln0Ddb1tm1SpgTgNescre1Kln