Jeong M. Kim, et.al., Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice., Nature immunology, 2007, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/17136045

Jeong M. Kim, et.al., Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice., Nature immunology, 2007, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698131

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• bradykinesia_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0005156I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• decreased T cell number_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0005018I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• increased susceptibility to autoimmune disorder_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0005350I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• lung inflammation_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0001861I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• enlarged spleen_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• abnormal dendritic cell physiology_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0002376I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• scaly skin_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0001192I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• increased sensitivity to induced morbidity/mortality_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0009763I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• conjunctivitis_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0001852I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• lung inflammation_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0001861I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• weight loss_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0001263I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• increased susceptibility to autoimmune disorder_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0005350I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• lymph node inflammation_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0003865I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• lymph node inflammation_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0003865I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• lymph node inflammation_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0003865I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• dermatitis_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0001194I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• enlarged spleen_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• increased dendritic cell number_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0008126I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• enlarged spleen_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• liver inflammation_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0001860I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• dermatitis_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0001194I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• dermatitis_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0001194I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• increased susceptibility to autoimmune disorder_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0005350I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• scaly skin_Foxp3<tm1.1Ayr>/Foxp3<tm1.1Ayr>
  http://metadb.riken.jp/0001192I129S1Sv129X1SvJC57BL6Foxp3tm11AyrFoxp3tm11AyrFoxp3tm11Ayr
• lung inflammation_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0001861I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• abnormal CD4-positive, alpha-beta T cell physiology_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0005463I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• liver inflammation_Foxp3<tm1.1Ayr>/Y
  http://metadb.riken.jp/0001860I129S1Sv129X1SvJC57BL6Foxp3tm11AyrYFoxp3tm11Ayr
• cachexia_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0005150I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr
• liver inflammation_Foxp3<tm3(DTR/GFP)Ayr>/Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/0001860I129S1Sv129X1SvJC57BL6Foxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyrFoxp3tm3DTRGFPAyr

class

http://purl.org/net/cito/citesAsAuthority

• Foxp3<tm3(DTR/GFP)Ayr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3698131