Naoko. Shima, et.al., A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice., Nature genetics, 2007, 39

http://rdf.ncbi.nlm.nih.gov/pubmed/17143284

Naoko. Shima, et.al., A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice., Nature genetics, 2007, 39

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mcm4<chaos3>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696791
• Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696796

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased cell proliferation_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0000352IC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• increased mammary adenocarcinoma incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0001883C3B6Mcm4chaos3Mcm4chaos3Mcm4chaos3Mcm4chaos3
• increased lung adenocarcinoma incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002027C3B6Mcm4chaos3Mcm4chaos3Mcm4chaos3Mcm4chaos3
• no abnormal phenotype detected_Mcm4<Gt(RRE056)Byg>/Mcm4<+>
  http://metadb.riken.jp/0002169I129P2OlaHsdMcm4GtRRE056BygMcm4Mcm4GtRRE056BygMcm4
• abnormal erythrocyte morphology_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0002447IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal cell cycle_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0003077B6CgMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056BygMcm4GtRRE056BygMcm4chaos3
他14件を見る
• abnormal cell cycle_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0003077IC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal cell nucleus morphology_Mcm4<chaos3>/Mcm4<+>
  http://metadb.riken.jp/0003111IC57BL6JMcm4chaos3Mcm4Mcm4Mcm4chaos3
• abnormal cell nucleus morphology_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0003111IC57BL6JMcm4chaos3Mcm4chaos3Mcm4chaos3
• abnormal digestive system development_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0003119I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056Byg
• increased hepatocellular carcinoma incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0003331C3B6Mcm4chaos3Mcm4chaos3Mcm4chaos3Mcm4chaos3
• embryonic growth retardation_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0003984B6CgMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056BygMcm4GtRRE056BygMcm4chaos3
• induced chromosome breakage_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0004030B6CgMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056BygMcm4GtRRE056BygMcm4chaos3
• fetal growth retardation_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0004201I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056Byg
• increased mammary gland tumor incidence_Mcm4<chaos3>/Mcm4<chaos3>
  http://metadb.riken.jp/0010299C3B6Mcm4chaos3Mcm4chaos3Mcm4chaos3Mcm4chaos3
• perinatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011090I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056Byg
• embryonic lethality between implantation and somite formation, complete penetrance_Mcm4<Gt(RRE056)Byg>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011096I129P2OlaHsdMcm4GtRRE056BygMcm4GtRRE056BygMcm4GtRRE056Byg
• lethality throughout fetal growth and development, complete penetrance_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011099B6CgMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056BygMcm4GtRRE056BygMcm4chaos3
• decreased fibroblast proliferation_Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0011704B6CgMcm4chaos3Mcm4GtRRE056BygMcm4chaos3Mcm4GtRRE056BygMcm4GtRRE056BygMcm4chaos3
• absent inner cell mass proliferation_Mcm4<Gt(RRE056)Byg>/Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/0012114I129P2OlaHsdMcm4GtRRE056BygMcm4GtRRE056BygMcm4GtRRE056Byg

class

http://purl.org/net/cito/citesAsAuthority

• Mcm4<chaos3>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696791
• Mcm4<Gt(RRE056)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696796