Jiasheng. Zhang, et.al., Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons., Nature neuroscience, 2007, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/17159989

Jiasheng. Zhang, et.al., Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons., Nature neuroscience, 2007, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased neuron apoptosis_Tgfb3<tm1Doe>/Tgfb3<tm1Doe>
  http://metadb.riken.jp/0003204I129P2OlaHsdC57BL6Tgfb3tm1DoeTgfb3tm1DoeTgfb3tm1Doe
• loss of dopaminergic neurons_Tgfb3<tm1Doe>/Tgfb3<tm1Doe>
  http://metadb.riken.jp/0003244I129P2OlaHsdC57BL6Tgfb3tm1DoeTgfb3tm1DoeTgfb3tm1Doe
• limb grasping_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0001513I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• abnormal gait_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0001406I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• abnormal voluntary movement_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0003491I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• short stride length_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0001407I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• impaired behavioral response to addictive substance_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0009750I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• decreased exploration in new environment_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0001417I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• decreased dopamine level_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0005643I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• abnormal response to novelty_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0003107I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• abnormal substantia nigra morphology_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0000836I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• decreased tegmentum size_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0006102I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• dystonia_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0005323I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• decreased neuron apoptosis_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0003204I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• impaired coordination_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0001405I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh
• decreased dopaminergic neuron number_Hipk2<tm1Ejh>/Hipk2<tm1Ejh>
  http://metadb.riken.jp/0011448I129X1SvJC57BL6Hipk2tm1EjhHipk2tm1EjhHipk2tm1Ejh