http://rdf.ncbi.nlm.nih.gov/pubmed/17183314

http://rdf.ncbi.nlm.nih.gov/pubmed/17183314

Laura J. Niedernhofer, et.al., A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis., Nature, 2006, 444

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased hepatocyte proliferation_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0004001I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• postnatal growth retardation_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• dystonia_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0005323I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• increased cellular sensitivity to oxidative stress_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0008412I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased circulating glucose level_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0005560I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased skeletal muscle mass_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0004819I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• ataxia_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0001393I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• abnormal kidney physiology_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0002136I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• acidosis_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0003031I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• premature aging_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0003786I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• abnormal DNA repair_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0008058I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• early cellular replicative senescence_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0008008I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• embryonic growth retardation_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased cell proliferation_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0000352I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• fetal growth retardation_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0004201I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• hepatic steatosis_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0002628I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• kyphosis_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• increased hepatocyte apoptosis_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0003887I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased bone mineral density_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0000063I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• abnormal postnatal growth_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0001731I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• postnatal lethality, incomplete penetrance_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• increased liver triglyceride level_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0009355I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased circulating insulin-like growth factor I level_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0004701I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• increased urine protein level_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0002962I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh
• decreased circulating insulin level_Ercc1<tm1Jhjh>/Ercc1<tm1Jhjh>
  http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6FVBErcc1tm1JhjhErcc1tm1JhjhErcc1tm1Jhjh