Ping. Bu, et.al., Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos., Molecular and cellular biology, 2007, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17325035

Ping. Bu, et.al., Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos., Molecular and cellular biology, 2007, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kat2a<tm2Roth>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711317

class

http://purl.org/net/cito/citesAsAuthority

• Kat2a<tm2Roth>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711317

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• exencephaly_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000914I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• abnormal telencephalon development_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000934I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• abnormal midbrain morphology_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000897I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• embryonic growth retardation_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003984I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• embryonic lethality during organogenesis, incomplete penetrance_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011108I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• failure of somite differentiation_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0001690I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• open neural tube_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000929I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• decreased fibroblast proliferation_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0011704I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• decreased embryo size_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001698I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• decreased embryo size_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0001698I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• abnormal embryo turning_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001700I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• abnormal metencephalon morphology_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000847I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• abnormal somite development_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001688I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• incomplete rostral neuropore closure_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0000928I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• decreased embryonic tissue cell apoptosis_Kat2a<tm1Roth>/Kat2a<tm1Roth>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0013505I129S2SvPas129S7SvEvBrdC57BL6JKat2atm1RothKat2atm1RothTrp53tm1TyjTrp53tm1TyjKat2atm1RothTrp53tm1Tyj
• embryonic lethality during organogenesis, incomplete penetrance_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0011108I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth
• increased embryonic tissue cell apoptosis_Kat2a<tm2Roth>/Kat2a<tm2Roth>
  http://metadb.riken.jp/0013504I129S7SvEvBrdC57BL6JKat2atm2RothKat2atm2RothKat2atm2Roth