Anita S. Galvez, et.al., Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis., Circulation research, 2007, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/17332428

Anita S. Galvez, et.al., Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis., Circulation research, 2007, 100

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-Cast)1Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437429
• Tg(Myh6*/tetO-Capn1)L1Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437471
• Tg(Myh6*/tetO-Capn1)L3Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437470
• Tg(Myh6*/tetO-Capn1)L2Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437466

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-Cast)1Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437429
• Tg(Myh6*/tetO-Capn1)L1Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437471
• Tg(Myh6*/tetO-Capn1)L3Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437470
• Tg(Myh6*/tetO-Capn1)L2Gwd
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437466

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart rate_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0001629IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• abnormal heart left ventricle morphology_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0003921IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• dilated cardiomyopathy_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0002795IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• myocardial necrosis_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0006085IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• decreased physiological sensitivity to xenobiotic_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0008874IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• decreased heart rate_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0005333IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• increased heart weight_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0002833IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• decreased ventricle muscle contractility_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0005598IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• congestive heart failure_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0006138IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• decreased ventricle muscle contractility_Tg(Myh6*/tetO-Capn1)L2Gwd/0
  http://metadb.riken.jp/0005598IFVBNTgMyh6tetOCapn1L2Gwd0TgMyh6tetOCapn1L2Gwd
• abnormal myocardial fiber morphology_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0000278IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• premature death_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0002083IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• increased heart weight_Tg(Myh6*/tetO-Capn1)L2Gwd/0
  http://metadb.riken.jp/0002833IFVBNTgMyh6tetOCapn1L2Gwd0TgMyh6tetOCapn1L2Gwd
• premature death_Tg(Myh6*/tetO-Capn1)L2Gwd/0
  http://metadb.riken.jp/0002083IFVBNTgMyh6tetOCapn1L2Gwd0TgMyh6tetOCapn1L2Gwd
• heart inflammation_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0001853IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• abnormal heart left ventricle morphology_Tg(Myh6-Cast)1Gwd/0
  http://metadb.riken.jp/0003921IFVBNTgMyh6Cast1Gwd0TgMyh6Cast1Gwd
• decreased ventricle muscle contractility_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0005598IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• dilated heart ventricle_Tg(Myh6*/tetO-Capn1)L3Gwd/0
  http://metadb.riken.jp/0008022IFVBNTgMyh6tetOCapn1L3Gwd0TgMyh6tetOCapn1L3Gwd
• abnormal heart left ventricle morphology_Tg(Myh6*/tetO-Capn1)L2Gwd/0
  http://metadb.riken.jp/0003921IFVBNTgMyh6tetOCapn1L2Gwd0TgMyh6tetOCapn1L2Gwd