William L. Holland, et.al., Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance., Cell metabolism, 2007, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/17339025

William L. Holland, et.al., Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance., Cell metabolism, 2007, 5

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal growth retardation_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0001732I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• increased insulin sensitivity_Degs1<Gt(OST368559)Lex>/Degs1<+>
  http://metadb.riken.jp/0002891I129S5SvEvBrdDegs1GtOST368559LexDegs1Degs1Degs1GtOST368559Lex
• decreased liver function_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0003325I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• sparse hair_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0000416I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• preweaning lethality, incomplete penetrance_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0011110I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• increased circulating alanine transaminase level_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0002941I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• increased circulating bilirubin level_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0005344I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• decreased bone mineral content_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0010124I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• decreased body length_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0001258I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• abnormal ceramide level_Degs1<Gt(OST368559)Lex>/Degs1<+>
  http://metadb.riken.jp/0012232I129S5SvEvBrdDegs1GtOST368559LexDegs1Degs1Degs1GtOST368559Lex
• decreased body size_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0001265I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• premature death_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0002083I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• increased muscle cell glucose uptake_Degs1<Gt(OST368559)Lex>/Degs1<+>
  http://metadb.riken.jp/0030021I129S5SvEvBrdDegs1GtOST368559LexDegs1Degs1Degs1GtOST368559Lex
• abnormal ceramide level_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0012232I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• decreased body weight_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0001262I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• decreased bone mineral density_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0000063I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• decreased lean body mass_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0003961I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• tremors_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0000745I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• abnormal hematopoietic system morphology/development_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0002396I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• increased circulating alkaline phosphatase level_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0002968I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex
• scaly skin_Degs1<Gt(OST368559)Lex>/Degs1<Gt(OST368559)Lex>
  http://metadb.riken.jp/0001192I129S5SvEvBrdDegs1GtOST368559LexDegs1GtOST368559LexDegs1GtOST368559Lex