Ralph. Gareus, et.al., Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation., Nature cell biology, 2007, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/17351639

Ralph. Gareus, et.al., Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation., Nature cell biology, 2007, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Chuk<tm1.1Mpa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3714161
• Chuk<tm1Mpa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3714160

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal limb morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0002109IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• impaired skin barrier function_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0002796IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• decreased circulating free fatty acid level_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0002702IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal keratinocyte differentiation_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0002656IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal epidermis stratum corneum morphology_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0001240IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal head morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0000432IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• thick epidermis_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0001219IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• abnormal skin morphology_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0002060IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal presphenoid bone morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0004448IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• abnormal epidermis stratum basale morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0001231IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• perinatal lethality, complete penetrance_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0011089IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• shiny skin_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0001196IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal xiphoid process morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0000159IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• abnormal keratinocyte differentiation_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0002656IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• abnormal skeleton morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0005508IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• cleft palate_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0000111IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• neonatal lethality, complete penetrance_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0011087IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• weight loss_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0001263IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal skin condition_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0001191IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal epidermal layer morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0001216IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• increased cholesterol level_Chuk<tm1Mpa>/Chuk<tm1Mpa>,Tg(KRT14-cre)1Cgn/?
  http://metadb.riken.jp/0003982IC57BL6Chuktm1MpaChuktm1MpaTgKRT14cre1CgnTgKRT14cre1CgnChuktm1Mpa
• abnormal tail morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0002111IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa
• abnormal vomer bone morphology_Chuk<tm1.1Mpa>/Chuk<tm1.1Mpa>
  http://metadb.riken.jp/0000098IC57BL6Chuktm11MpaChuktm11MpaChuktm11Mpa

class

http://purl.org/net/cito/citesAsAuthority

• Chuk<tm1.1Mpa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3714161
• Chuk<tm1Mpa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3714160