Carmine. Settembre, et.al., Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

http://rdf.ncbi.nlm.nih.gov/pubmed/17360554

Carmine. Settembre, et.al., Systemic inflammation and neurodegeneration in a mouse model of multiple sulfatase deficiency., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707232

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased hepatocyte apoptosis_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0003887I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• decreased body size_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• CNS inflammation_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0006082I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• postnatal lethality, incomplete penetrance_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal long bone epiphysis morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000131I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal cerebellar cortex morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0004097I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• premature death_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• limb grasping_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0001513I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal thoracic vertebrae morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0003047I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• kyphosis_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• postnatal growth retardation_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal long bone metaphysis morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000133I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal craniofacial morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000428I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal microglial cell morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000136I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal joint morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0002932I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• decreased length of long bones_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0004686I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• increased macrophage cell number_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0005425I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• seizures_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0002064I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• decreased Purkinje cell number_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000880I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• tremors_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000745I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• short limbs_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0000547I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• increased neuron apoptosis_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0003203I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• decreased cranium height_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0008525I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal astrocyte morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0002182I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg
• abnormal macrophage morphology_Sumf1<Gt(RST760)Byg>/Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/0002446I129P2OlaHsdC57BL6Sumf1GtRST760BygSumf1GtRST760BygSumf1GtRST760Byg

class

http://purl.org/net/cito/citesAsAuthority

• Sumf1<Gt(RST760)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707232