Tomoaki. Hoshino, et.al., Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13., American journal of respiratory and critical care medicine, 2007, 176

http://rdf.ncbi.nlm.nih.gov/pubmed/17400729

Tomoaki. Hoshino, et.al., Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13., American journal of respiratory and critical care medicine, 2007, 176

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-cat,-Il18)#Thos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688534
• Tg(SFTPC-Il18)AThos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688493

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-cat,-Il18)#Thos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688534
• Tg(SFTPC-Il18)AThos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5688493

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• overexpanded pulmonary alveoli_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001183B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal lung volume_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001942B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• enlarged heart_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0000274B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• dilated heart right ventricle_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0002754B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• increased interleukin-13 secretion_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0008672B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• enlarged spleen_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0000691B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal pulmonary alveolus wall morphology_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0010903B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• lung inflammation_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001861B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal pulmonary alveolus morphology_Tg(CAG-cat,-Il18)#Thos/0,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0002270I129C57BL6TgCAGcatIl18Thos0TgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgCAGcatIl18ThosTgSFTPCrtTA5JawTgtetOcre1Jaw
• increased interferon-gamma secretion_Tg(CAG-cat,-Il18)#Thos/0,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0008566I129C57BL6TgCAGcatIl18Thos0TgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgCAGcatIl18ThosTgSFTPCrtTA5JawTgtetOcre1Jaw
• abnormal cardiovascular system physiology_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001544B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• emphysema_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001958B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal lung volume_Ifng<tm1Ts>/Ifng<tm1Ts>,Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001942I129S7SvEvBrdC57BL6C57BL6NDBA2Ifngtm1TsIfngtm1TsTgSFTPCIl18AThos0Ifngtm1TsTgSFTPCIl18AThos
• increased interferon-gamma secretion_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0008566B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal lung compliance_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0002333B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal pulmonary alveolus morphology_Il13<tm2Anjm>/Il13<tm2Anjm>,Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0002270I129P2OlaHsdC57BL6C57BL6NDBA2Il13tm2AnjmIl13tm2AnjmTgSFTPCIl18AThos0TgSFTPCIl18AThosIl13tm2Anjm
• increased right ventricle systolic pressure_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0010758B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal pulmonary alveolus morphology_Ifng<tm1Ts>/Ifng<tm1Ts>,Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0002270I129S7SvEvBrdC57BL6C57BL6NDBA2Ifngtm1TsIfngtm1TsTgSFTPCIl18AThos0Ifngtm1TsTgSFTPCIl18AThos
• interstitial pneumonia_Tg(CAG-cat,-Il18)#Thos/0,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0001862I129C57BL6TgCAGcatIl18Thos0TgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgCAGcatIl18ThosTgSFTPCrtTA5JawTgtetOcre1Jaw
• abnormal spleen morphology_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0000689B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• pulmonary hypertension_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0003548B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• heart right ventricle hypertrophy_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0000276B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• abnormal pulmonary alveolus morphology_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0002270B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• lung inflammation_Ifng<tm1Ts>/Ifng<tm1Ts>,Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001861I129S7SvEvBrdC57BL6C57BL6NDBA2Ifngtm1TsIfngtm1TsTgSFTPCIl18AThos0Ifngtm1TsTgSFTPCIl18AThos
• increased right ventricle diastolic pressure_Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0008777B6NCgTgSFTPCIl18AThosTgSFTPCIl18AThos0TgSFTPCIl18AThos
• emphysema_Ifng<tm1Ts>/Ifng<tm1Ts>,Tg(SFTPC-Il18)AThos/0
  http://metadb.riken.jp/0001958I129S7SvEvBrdC57BL6C57BL6NDBA2Ifngtm1TsIfngtm1TsTgSFTPCIl18AThos0Ifngtm1TsTgSFTPCIl18AThos