Hongwei. Yu, et.al., Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice., BMC developmental biology, 2007, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/17408495

Hongwei. Yu, et.al., Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice., BMC developmental biology, 2007, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-DHCR7)2Hoyu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819682

class

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-DHCR7)2Hoyu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819682

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hypotonia_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0004144I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• decreased brain cholesterol level_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0010161I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• neonatal lethality, complete penetrance_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>
  http://metadb.riken.jp/0011087I129P2OlaHsdDhcr7tm1GstDhcr7tm1GstDhcr7tm1Gst
• abnormal suckling behavior_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0001436I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• decreased liver cholesterol level_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0010026I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• postnatal lethality, complete penetrance_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• decreased cholesterol level_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0003983I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• decreased circulating cholesterol level_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0005179I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• impaired lung alveolus development_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>,Tg(APOE-DHCR7)2Hoyu/0
  http://metadb.riken.jp/0006027I129P2OlaHsdC57BLC57BL6JFVBNDhcr7tm1GstDhcr7tm1GstTgAPOEDHCR72Hoyu0Dhcr7tm1GstTgAPOEDHCR72Hoyu
• impaired lung alveolus development_Dhcr7<tm1Gst>/Dhcr7<tm1Gst>
  http://metadb.riken.jp/0006027I129P2OlaHsdDhcr7tm1GstDhcr7tm1GstDhcr7tm1Gst