Jose M. Galan-Caridad, et.al., Zfx controls the self-renewal of embryonic and hematopoietic stem cells., Cell, 2007, 129

http://rdf.ncbi.nlm.nih.gov/pubmed/17448993

Jose M. Galan-Caridad, et.al., Zfx controls the self-renewal of embryonic and hematopoietic stem cells., Cell, 2007, 129

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Zfx<tm1.1Reiz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848796
• Zfx<tm1.2Reiz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848798

class

http://purl.org/net/cito/citesAsAuthority

• Zfx<tm1.1Reiz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848796
• Zfx<tm1.2Reiz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848798

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal common lymphocyte progenitor cell morphology_Zfx<tm1.1Reiz>/Y,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008249I129S6SvEvTacC57BL6CBAZfxtm11ReizYTgMx1cre1Cgn0Zfxtm11ReizTgMx1cre1Cgn
• abnormal extraembryonic tissue morphology_Zfx<tm1.2Reiz>/Zfx<tm1.2Reiz>
  http://metadb.riken.jp/0002086I129S6SvEvTacC57BL6DBA2Zfxtm12ReizZfxtm12ReizZfxtm12Reiz
• embryonic lethality during organogenesis, complete penetrance_Zfx<tm1.2Reiz>/Y
  http://metadb.riken.jp/0011098I129S6SvEvTacC57BL6DBA2Zfxtm12ReizYZfxtm12Reiz
• decreased lymphocyte cell number_Zfx<tm1.1Reiz>/Y,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005016I129S6SvEvTacC57BL6CBAZfxtm11ReizYTgMx1cre1Cgn0Zfxtm11ReizTgMx1cre1Cgn
• decreased hematopoietic stem cell number_Zfx<tm1.1Reiz>/Y,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004810I129S6SvEvTacC57BL6CBAZfxtm11ReizYTgMx1cre1Cgn0Zfxtm11ReizTgMx1cre1Cgn
• abnormal extraembryonic tissue morphology_Zfx<tm1.2Reiz>/Y
  http://metadb.riken.jp/0002086I129S6SvEvTacC57BL6DBA2Zfxtm12ReizYZfxtm12Reiz
• embryonic lethality during organogenesis, complete penetrance_Zfx<tm1.2Reiz>/Zfx<tm1.2Reiz>
  http://metadb.riken.jp/0011098I129S6SvEvTacC57BL6DBA2Zfxtm12ReizZfxtm12ReizZfxtm12Reiz
• neonatal lethality, complete penetrance_Zfx<tm1.1Reiz>/Y,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0011087I129S4SvJaeSor129S6SvEvTacZfxtm11ReizYMeox2tm1creSorMeox2Zfxtm11ReizMeox2Meox2tm1creSor
• decreased T cell number_Zfx<tm1.1Reiz>/Y,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0005018I129S6SvEvTacC3HC57BL6Zfxtm11ReizYTgTekcre12Flv0TgTekcre12FlvZfxtm11Reiz
• abnormal hematopoietic system physiology_Zfx<tm1.1Reiz>/Y,Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001545I129Sv129S6SvEvTacZfxtm11ReizYGtROSA26Sortm1creERT2ThlGtROSA26SorGtROSA26Sortm1creERT2ThlZfxtm11ReizGtROSA26Sor
• abnormal common lymphocyte progenitor cell morphology_Zfx<tm1.1Reiz>/Y,Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008249I129Sv129S6SvEvTacZfxtm11ReizYGtROSA26Sortm1creERT2ThlGtROSA26SorGtROSA26Sortm1creERT2ThlZfxtm11ReizGtROSA26Sor
• abnormal hematopoietic system physiology_Zfx<tm1.1Reiz>/Y,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0001545I129S6SvEvTacC3HC57BL6Zfxtm11ReizYTgTekcre12Flv0TgTekcre12FlvZfxtm11Reiz
• decreased mature B cell number_Zfx<tm1.1Reiz>/Y,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008211I129S6SvEvTacC3HC57BL6Zfxtm11ReizYTgTekcre12Flv0TgTekcre12FlvZfxtm11Reiz
• impaired hematopoiesis_Zfx<tm1.1Reiz>/Y,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001606I129S6SvEvTacC57BL6CBAZfxtm11ReizYTgMx1cre1Cgn0Zfxtm11ReizTgMx1cre1Cgn
• neonatal lethality, complete penetrance_Zfx<tm1.1Reiz>/Zfx<tm1.1Reiz>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0011087I129S4SvJaeSor129S6SvEvTacZfxtm11ReizZfxtm11ReizMeox2tm1creSorMeox2Meox2Zfxtm11ReizMeox2tm1creSor
• decreased hematopoietic stem cell number_Zfx<tm1.2Reiz>/Y
  http://metadb.riken.jp/0004810I129S6SvEvTacC57BL6DBA2Zfxtm12ReizYZfxtm12Reiz
• decreased hematopoietic stem cell number_Zfx<tm1.1Reiz>/Y,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0004810I129S6SvEvTacC3HC57BL6Zfxtm11ReizYTgTekcre12Flv0TgTekcre12FlvZfxtm11Reiz
• abnormal hematopoietic system physiology_Zfx<tm1.1Reiz>/Y,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001545I129S6SvEvTacC57BL6CBAZfxtm11ReizYTgMx1cre1Cgn0Zfxtm11ReizTgMx1cre1Cgn
• abnormal common lymphocyte progenitor cell morphology_Zfx<tm1.1Reiz>/Y,Tg(Tek-cre)12Flv/0
  http://metadb.riken.jp/0008249I129S6SvEvTacC3HC57BL6Zfxtm11ReizYTgTekcre12Flv0TgTekcre12FlvZfxtm11Reiz
• decreased hematopoietic stem cell number_Zfx<tm1.1Reiz>/Y,Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004810I129Sv129S6SvEvTacZfxtm11ReizYGtROSA26Sortm1creERT2ThlGtROSA26SorGtROSA26Sortm1creERT2ThlZfxtm11ReizGtROSA26Sor
• decreased hematopoietic stem cell number_Zfx<tm1.2Reiz>/Zfx<tm1.2Reiz>
  http://metadb.riken.jp/0004810I129S6SvEvTacC57BL6DBA2Zfxtm12ReizZfxtm12ReizZfxtm12Reiz

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD07065
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07065