Atsuko. Nakai, et.al., The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress., Nature medicine, 2007, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/17450150

Atsuko. Nakai, et.al., The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress., Nature medicine, 2007, 13

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased physiological sensitivity to xenobiotic_Atg5<tm1Myok>/Atg5<tm1Myok>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008873I129SSvEv129S4SvJaeAtg5tm1MyokAtg5tm1MyokMyl2tm1creKrcMyl2Myl2tm1creKrcAtg5tm1MyokMyl2
• no abnormal phenotype detected_Atg5<tm1Myok>/Atg5<tm1Myok>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0002169I129SSvEvC57BL6FVBNAtg5tm1MyokAtg5tm1MyokTgMyh6cre2182MdsTgMyh6cre2182MdsAtg5tm1Myok
• increased heart weight_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0002833I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok
• enlarged myocardial fiber_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0004564I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok
• increased sensitivity to induced morbidity/mortality_Atg5<tm1Myok>/Atg5<tm1Myok>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0009763I129SSvEv129S4SvJaeAtg5tm1MyokAtg5tm1MyokMyl2tm1creKrcMyl2Myl2tm1creKrcAtg5tm1MyokMyl2
• abnormal myocardial fiber physiology_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0004215I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok
• increased lung weight_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0005630I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok
• dilated heart left ventricle_Atg5<tm1Myok>/Atg5<tm1Myok>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002753I129SSvEv129S4SvJaeAtg5tm1MyokAtg5tm1MyokMyl2tm1creKrcMyl2Myl2tm1creKrcAtg5tm1MyokMyl2
• abnormal cardiac muscle contractility_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0002972I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok
• abnormal cardiovascular system physiology_Atg5<tm1Myok>/Atg5<tm1Myok>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001544I129SSvEv129S4SvJaeAtg5tm1MyokAtg5tm1MyokMyl2tm1creKrcMyl2Myl2tm1creKrcAtg5tm1MyokMyl2
• congestive heart failure_Atg5<tm1Myok>/Atg5<tm1Myok>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0006138I129SSvEv129S4SvJaeAtg5tm1MyokAtg5tm1MyokMyl2tm1creKrcMyl2Myl2tm1creKrcAtg5tm1MyokMyl2
• dilated heart left ventricle_Atg5<tm1Myok>/Atg5<tm1Myok>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/?
  http://metadb.riken.jp/0002753I129SSvEvFVBNAtg5tm1MyokAtg5tm1MyokA1cfTgMyh6creEsr11JmkA1cfTgMyh6creEsr11JmkAtg5tm1Myok

BRC マウスの系統

http://purl.org/dc/terms/references

• GFP-LC3#53
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC00806

BRC マウスの系統

http://metadb.riken.jp/db/rikenbrc_mouse/publications

• GFP-LC3#53
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC00806