Sandra. Niendorf, et.al., Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo., Molecular and cellular biology, 2007, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17452457

Sandra. Niendorf, et.al., Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo., Molecular and cellular biology, 2007, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Usp8<tm1.1Kpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3716283
• Usp8<tm1.2Kpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3716285

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• jaundice_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000611I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• premature death_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• hepatic necrosis_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001654I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• liver failure_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003326I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• increased hepatocyte apoptosis_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003887I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• increased circulating bilirubin level_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005344I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• abnormal embryo development_Usp8<tm1.2Kpk>/Usp8<tm1.2Kpk>
  http://metadb.riken.jp/0001672I129P2OlaHsdFVBNUsp8tm12KpkUsp8tm12KpkUsp8tm12Kpk
• abnormal hepatocyte morphology_Usp8<tm1.1Kpk>/Usp8<tm1.1Kpk>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000607I129P2OlaHsdC57BL6CBAFVBNUsp8tm11KpkUsp8tm11KpkTgMx1cre1Cgn0Usp8tm11KpkTgMx1cre1Cgn
• embryonic lethality, complete penetrance_Usp8<tm1.2Kpk>/Usp8<tm1.2Kpk>
  http://metadb.riken.jp/0011092I129P2OlaHsdFVBNUsp8tm12KpkUsp8tm12KpkUsp8tm12Kpk
• abnormal dorsal-ventral axis patterning_Usp8<tm1.2Kpk>/Usp8<tm1.2Kpk>
  http://metadb.riken.jp/0001704I129P2OlaHsdFVBNUsp8tm12KpkUsp8tm12KpkUsp8tm12Kpk
• embryonic growth retardation_Usp8<tm1.2Kpk>/Usp8<tm1.2Kpk>
  http://metadb.riken.jp/0003984I129P2OlaHsdFVBNUsp8tm12KpkUsp8tm12KpkUsp8tm12Kpk
• abnormal heart development_Usp8<tm1.2Kpk>/Usp8<tm1.2Kpk>
  http://metadb.riken.jp/0000267I129P2OlaHsdFVBNUsp8tm12KpkUsp8tm12KpkUsp8tm12Kpk

class

http://purl.org/net/cito/citesAsAuthority

• Usp8<tm1.1Kpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3716283
• Usp8<tm1.2Kpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3716285