Andreas. Zembrzycki, et.al., Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain., Neural development, 2007, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/17470284

Andreas. Zembrzycki, et.al., Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain., Neural development, 2007, 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sp8<tm2.1Aman>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4455192

class

http://purl.org/net/cito/citesAsAuthority

• Sp8<tm2.1Aman>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4455192

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal brain internal capsule morphology_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0008128I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal lateral ventricle morphology_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000823I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• increased neuron apoptosis_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003203I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• telencephalon hypoplasia_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000785I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal basal ganglion morphology_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0006007I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• neonatal lethality, complete penetrance_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0011087I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal telencephalon development_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000934I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• forebrain hypoplasia_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000784I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal cortical plate morphology_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0008439I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal forebrain development_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0003232I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• thin cortical plate_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0008441I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal olfactory bulb development_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0002739I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal neuronal precursor proliferation_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0004948I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• holoprosencephaly_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0005157I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm
• abnormal craniofacial morphology_Sp8<tm2.1Aman>/Sp8<tm2.1Aman>,Foxg1<tm1(cre)Skm>/Foxg1<+>
  http://metadb.riken.jp/0000428I129P2OlaHsdC57BL6Sp8tm21AmanSp8tm21AmanFoxg1tm1creSkmFoxg1Foxg1Sp8tm21AmanFoxg1tm1creSkm