Benjamin L. Allen, et.al., The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development., Genes & development, 2007, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/17504941

Benjamin L. Allen, et.al., The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development., Genes & development, 2007, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased neuronal precursor cell number_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0004981I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• oligodactyly_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000565IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal craniofacial morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000428I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal limb morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0002109I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• decreased neuronal precursor cell number_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0004981IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• oligodactyly_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<+>
  http://metadb.riken.jp/0000565I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1Cdontm2RskGas1tm2FanGas1
• holoprosencephaly_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0005157I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• syndactyly_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000564IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal innervation_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0002184I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• increased neuronal precursor cell number_Gas1<tm2Fan>/Gas1<+>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0004980I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1Shhtm1ChgShhShhGas1Gas1tm2FanShhtm1Chg
• abnormal craniofacial development_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0003935I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal vertebrae morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000137I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• decreased fetal size_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0004200I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• cervical vertebral fusion_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0004620I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal floor plate morphology_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000925IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• oligodactyly_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0000565I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• abnormal intervertebral disk morphology_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0004173I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• absent maxilla_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0004539I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal maxilla morphology_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000455IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal vertebral body morphology_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0000141I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• syndactyly_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<+>
  http://metadb.riken.jp/0000564I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1Cdontm2RskGas1tm2FanGas1
• short mandible_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0000088I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• abnormal vertebral body morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<+>
  http://metadb.riken.jp/0000141I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1Cdontm2RskGas1tm2FanGas1
• oligodactyly_Cdon<tm2Rsk>/Cdon<+>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000565I129C57BL6JCdontm2RskCdonGas1tm2FanGas1tm2FanGas1tm2FanCdontm2RskCdon
• notochord degeneration_Shh<tm1Amc>/Shh<tm1Amc>
  http://metadb.riken.jp/0004712I129S1Sv129X1SvJShhtm1AmcShhtm1AmcShhtm1Amc
• abnormal nose morphology_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0002233IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal nose morphology_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0002233I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• small parietal bone_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0004418IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal vertebral body morphology_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000141IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• abnormal vertebral body morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000141I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal nose morphology_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0002233I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal vertebrae morphology_Shh<tm1Amc>/Shh<tm1Amc>
  http://metadb.riken.jp/0000137I129S1Sv129X1SvJShhtm1AmcShhtm1AmcShhtm1Amc
• abnormal craniofacial morphology_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0000428I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh
• holoprosencephaly_Shh<tm1Amc>/Shh<tm1Amc>
  http://metadb.riken.jp/0005157I129S1Sv129X1SvJShhtm1AmcShhtm1AmcShhtm1Amc
• absent mandible_Cdon<tm2Rsk>/Cdon<tm2Rsk>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000087I129C57BL6JCdontm2RskCdontm2RskGas1tm2FanGas1tm2FanCdontm2RskGas1tm2Fan
• abnormal tympanic ring morphology_Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000030IC57BL6JGas1tm2FanGas1tm2FanGas1tm2Fan
• syndactyly_Cdon<tm2Rsk>/Cdon<+>,Gas1<tm2Fan>/Gas1<tm2Fan>
  http://metadb.riken.jp/0000564I129C57BL6JCdontm2RskCdonGas1tm2FanGas1tm2FanGas1tm2FanCdontm2RskCdon
• abnormal floor plate morphology_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>
  http://metadb.riken.jp/0000925I129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhGas1tm2FanShhtm1ChgShh