Jianjun. Bao, et.al., Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice., The Journal of biological chemistry, 2007, 282

http://rdf.ncbi.nlm.nih.gov/pubmed/17519229

Jianjun. Bao, et.al., Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice., The Journal of biological chemistry, 2007, 282

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775953

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, incomplete penetrance_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0011109I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• decreased cardiac muscle contractility_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0005140I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• cardiac interstitial fibrosis_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0005608I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• dilated cardiomyopathy_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0002795I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• abnormal spinal cord morphology_Myh10<tm2Rsad>/Myh10<tm2Rsad>
  http://metadb.riken.jp/0000955I129S4SvJaeMyh10tm2RsadMyh10tm2RsadMyh10tm2Rsad
• double outlet right ventricle_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0000284I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• hydroencephaly_Myh10<tm2Rsad>/Myh10<tm2Rsad>
  http://metadb.riken.jp/0001891I129S4SvJaeMyh10tm2RsadMyh10tm2RsadMyh10tm2Rsad
• abnormal neuronal migration_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0006009I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• no abnormal phenotype detected_Myh10<tm8Rsad>/Myh10<tm8Rsad>
  http://metadb.riken.jp/0002169I129Myh10tm8RsadMyh10tm8RsadMyh10tm8Rsad
• cardiac hypertrophy_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0001625I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• ventricular septal defect_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0010402I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• abnormal fetal cardiomyocyte morphology_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0008788I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• decreased survivor rate_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0008770I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• abnormal cerebellar foliation_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0000857I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad
• enlarged myocardial fiber_Myh10<tm6(Myh9/GFP)Rsad>/Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/0004564I129S6SvEvTacC57BL6Myh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsadMyh10tm6Myh9GFPRsad

class

http://purl.org/net/cito/citesAsAuthority

• Myh10<tm6(Myh9/GFP)Rsad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775953