Anja. Uhmann, et.al., The Hedgehog receptor Patched controls lymphoid lineage commitment., Blood, 2007, 110

http://rdf.ncbi.nlm.nih.gov/pubmed/17536012

Anja. Uhmann, et.al., The Hedgehog receptor Patched controls lymphoid lineage commitment., Blood, 2007, 110

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptch1<tm1Hahn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764517

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pre-B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008209I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• decreased lymphocyte cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005016I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• increased mature B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008210I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• abnormal thymus lobule morphology_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002367I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• increased double-negative T cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005090I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• decreased double-positive T cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005092I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• increased single-positive T cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008082I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• decreased transitional stage B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008190I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• thymus hypoplasia_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001823I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• no abnormal phenotype detected_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnPtch1tm1Hahn
• decreased immature B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008215I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• decreased B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005017I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• abnormal double-negative T cell morphology_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002407I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• increased neutrophil cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000219I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• abnormal hematopoietic system morphology/development_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002396I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor
• increased B cell number_Ptch1<tm1Hahn>/Ptch1<tm1Hahn>,Gt(ROSA)26Sor<tm2(cre/ERT2)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S1Sv129X1SvJC57BL6Ptch1tm1HahnPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26SorPtch1tm1HahnGtROSA26Sortm2creERT2BrnGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Ptch1<tm1Hahn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764517