Imme. Krüger, et.al., Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects., Developmental dynamics : an official publication of the American Association of Anatomists, 2007, 236

http://rdf.ncbi.nlm.nih.gov/pubmed/17584888

Imme. Krüger, et.al., Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects., Developmental dynamics : an official publication of the American Association of Anatomists, 2007, 236

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• skin edema_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001786I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal placenta morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001711I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased placenta weight_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0004921I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal spongiotrophoblast cell morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0008959I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased body size_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal spongiotrophoblast cell morphology_Sp3<tm1Sus>/Sp3<tm1Sus>
  http://metadb.riken.jp/0008959I129P2OlaHsdC57BL6Sp3tm1SusSp3tm1SusSp3tm1Sus
• anemia_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001577I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal cranium morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0000438I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased spongiotrophoblast size_Sp3<tm1Sus>/Sp3<tm1Sus>
  http://metadb.riken.jp/0012099I129P2OlaHsdC57BL6Sp3tm1SusSp3tm1SusSp3tm1Sus
• disorganized placental labyrinth_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0011527I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal trophoblast glycogen cell morphology_Sp3<tm1Sus>/Sp3<tm1Sus>
  http://metadb.riken.jp/0008958I129P2OlaHsdC57BL6Sp3tm1SusSp3tm1SusSp3tm1Sus
• abnormal phalanx morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0005306I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• lethality at weaning, complete penetrance_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0011083I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal lung morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001175I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased spongiotrophoblast size_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0012099I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased erythroid progenitor cell number_Sp1<tm1Phi>/Sp1<+>
  http://metadb.riken.jp/0008973I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp1tm1PhiSp1
• decreased body size_Sp1<tm1Phi>/Sp1<+>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp1tm1PhiSp1
• abnormal erythroid progenitor cell morphology_Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0008801I129P2OlaHsdC57BL6Sp3tm1SusSp3Sp3Sp3tm1Sus
• decreased body size_Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Sp3tm1SusSp3Sp3Sp3tm1Sus
• pallor_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0003717I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• small liver_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0000601I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• anophthalmia_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0001293I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal placenta labyrinth morphology_Sp3<tm1Sus>/Sp3<tm1Sus>
  http://metadb.riken.jp/0001716I129P2OlaHsdC57BL6Sp3tm1SusSp3tm1SusSp3tm1Sus
• decreased erythroid progenitor cell number_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0008973I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• hypovolemia_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0010128I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased liver weight_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0003402I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• decreased trophoblast glycogen cell number_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0012109I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• lethality throughout fetal growth and development, incomplete penetrance_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0011109I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal liver sinusoid morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0008989I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• anophthalmia_Sp1<tm1Phi>/Sp1<+>
  http://metadb.riken.jp/0001293I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp1tm1PhiSp1
• decreased fetal weight_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0009431I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal erythropoiesis_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0000245I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal bone ossification_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0008271I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi
• abnormal placenta intervillous maternal lacunae morphology_Sp1<tm1Phi>/Sp1<+>,Sp3<tm1Sus>/Sp3<+>
  http://metadb.riken.jp/0011525I129P2OlaHsdC57BL6Sp1tm1PhiSp1Sp3tm1SusSp3Sp3Sp3tm1SusSp1Sp1tm1Phi