Amir. Pozner, et.al., Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis., BMC developmental biology, 2007, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/17626615

Amir. Pozner, et.al., Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis., BMC developmental biology, 2007, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm1Yg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760788

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal definitive hematopoiesis_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0002123EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• spinal hemorrhage_Runx1<tm1Yg>/Runx1<tm2Spe>
  http://metadb.riken.jp/0006054EI129SvorI129SvICRorI129SvMF1Runx1tm1YgRunx1tm2SpeRunx1tm1YgRunx1tm2Spe
• thymus hypoplasia_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0001823EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• abnormal thymus corticomedullary boundary morphology_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0009543EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• small thymus_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0000706EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• intracranial hemorrhage_Runx1<tm1Yg>/Runx1<tm2Spe>
  http://metadb.riken.jp/0001915EI129SvorI129SvICRorI129SvMF1Runx1tm1YgRunx1tm2SpeRunx1tm1YgRunx1tm2Spe
• increased thymocyte apoptosis_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0009541EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• abnormal T cell differentiation_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0002145EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• abnormal thymus lobule morphology_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0002367EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• abnormal leukopoiesis_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0005460EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• thymus cysts_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0014130EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• postnatal lethality, complete penetrance_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0011085EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• decreased single-positive T cell number_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0008083EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• decreased body size_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0001265EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• embryonic lethality during organogenesis, complete penetrance_Runx1<tm1Yg>/Runx1<tm2Spe>
  http://metadb.riken.jp/0011098EI129SvorI129SvICRorI129SvMF1Runx1tm1YgRunx1tm2SpeRunx1tm1YgRunx1tm2Spe
• internal hemorrhage_Runx1<tm1Yg>/Runx1<tm2Spe>
  http://metadb.riken.jp/0001634EI129SvorI129SvICRorI129SvMF1Runx1tm1YgRunx1tm2SpeRunx1tm1YgRunx1tm2Spe
• decreased T cell number_Runx1<tm1Yg>/Runx1<tm1Yg>,Tg(Lck-cre)1Jtak/?
  http://metadb.riken.jp/0005018EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgTgLckcre1JtakRunx1tm1YgTgLckcre1Jtak
• slow postnatal weight gain_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0008489EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• increased double-positive T cell number_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0005091EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg
• decreased thymocyte number_Runx1<tm1Yg>/Runx1<tm1Yg>
  http://metadb.riken.jp/0000715EI129Sv129S1Sv129X1SvJorI129S1Sv129X1SvJICRorI129S1Sv129X1SvJMF1Runx1tm1YgRunx1tm1YgRunx1tm1Yg

class

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm1Yg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760788