Robert V. Farese, et.al., Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes., The Journal of clinical investigation, 2007, 117

http://rdf.ncbi.nlm.nih.gov/pubmed/17641777

Robert V. Farese, et.al., Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes., The Journal of clinical investigation, 2007, 117

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prkci<tm1Rfar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720810

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating cholesterol level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005178I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating triglyceride level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0001552I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating leptin level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005669I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• decreased circulating HDL cholesterol level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0000186I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased circulating glucose level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005559I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased circulating leptin level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005669I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating LDL cholesterol level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0000182I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased circulating free fatty acid level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0001554I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• abnormal glucose homeostasis_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0002078I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• pancreatic islet hyperplasia_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005491I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• decreased cardiac cell glucose uptake_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0030020I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased susceptibility to autoimmune diabetes_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0004803I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• insulin resistance_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005331I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• decreased cardiac cell glucose uptake_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0030020I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• abnormal circulating lipid level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0003949I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating cholesterol level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005178I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• decreased circulating HDL cholesterol level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0000186I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating triglyceride level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0001552I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• insulin resistance_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005331I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• impaired glucose tolerance_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• decreased adipocyte glucose uptake_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0030017I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased food intake_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0011939I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• hepatic steatosis_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0002628I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased circulating insulin level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0002079I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased circulating glucose level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005559I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• decreased muscle cell glucose uptake_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0030022I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• impaired glucose tolerance_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating LDL cholesterol level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0000182I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased body weight_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0001260I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• pancreatic islet hyperplasia_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0005491I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• decreased muscle cell glucose uptake_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0030022I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• decreased adipocyte glucose uptake_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0030017I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• abnormal circulating lipid level_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0003949I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar
• increased body weight_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0001260I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• obese_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0001261I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• hepatic steatosis_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0002628I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating free fatty acid level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0001554I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• increased circulating insulin level_Prkci<tm1Rfar>/Prkci<+>,Tg(Ckmm-cre)5Khn/?
  http://metadb.riken.jp/0002079I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkciTgCkmmcre5KhnPrkciPrkcitm1RfarTgCkmmcre5Khn
• abnormal glucose homeostasis_Prkci<tm1Rfar>/Prkci<tm1Rfar>
  http://metadb.riken.jp/0002078I129P2OlaHsdC57BL6FVBPrkcitm1RfarPrkcitm1RfarPrkcitm1Rfar

class

http://purl.org/net/cito/citesAsAuthority

• Prkci<tm1Rfar>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720810