A. Farini, et.al., T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse., The Journal of pathology, 2007, 213

http://rdf.ncbi.nlm.nih.gov/pubmed/17668421

A. Farini, et.al., T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse., The Journal of pathology, 2007, 213

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired exercise endurance_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0012106IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• skeletal muscle fiber degeneration_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0009412IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• increased transforming growth factor level_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008837IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• abnormal vertebral column morphology_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0004703IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• impaired exercise endurance_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0012106IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• skeletal muscle fiber degeneration_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0009412IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• centrally nucleated skeletal muscle fibers_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0009404IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• increased skeletal muscle fiber diameter_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0009401IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• absent CD4-positive, alpha beta T cells_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0003790IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• skeletal muscle fibrosis_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0009419IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• centrally nucleated skeletal muscle fibers_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0009404IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• decreased transforming growth factor level_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0008838IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• reduced fertility_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0001921IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• increased skeletal muscle fiber diameter_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0009401IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• absent CD8-positive, alpha-beta T cells_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0000727IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• impaired skeletal muscle contractility_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0002841IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• skeletal muscle fibrosis_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0009419IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• decreased B cell number_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0005017IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid
• impaired skeletal muscle contractility_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0002841IC57BL10ScSnCB17DmdmdxDmdmdxDmdmdx
• abnormal vertebral column morphology_Dmd<mdx>/Dmd<mdx>,Prkdc<scid>/Prkdc<scid>
  http://metadb.riken.jp/0004703IC57BL10ScSnCB17DmdmdxDmdmdxPrkdcscidPrkdcscidDmdmdxPrkdcscid

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased transforming growth factor level in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005753
• muscle phenotype in RBRC06336
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016059
• abnormal vertebral column morphology in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005739
• muscle phenotype in RBRC01300
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014998
• increased skeletal muscle fiber diameter in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010947
• muscle phenotype in RBRC01346
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017627
• skeletal muscle fiber degeneration in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010697
• muscle phenotype in RBRC02775
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020436
• impaired exercise endurance in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005764