Jukka. Kero, et.al., Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development., The Journal of clinical investigation, 2007, 117

http://rdf.ncbi.nlm.nih.gov/pubmed/17694176

Jukka. Kero, et.al., Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development., The Journal of clinical investigation, 2007, 117

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Tg-cre)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:3796561

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Tg-cre)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:3796561

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal thyroid gland morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0000681I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff
• abnormal thyroid physiology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0002876I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff
• decreased activity of thyroid_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0003503I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff
• abnormal thyroid follicular cell morphology_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0004697I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff
• increased circulating thyroid-stimulating hormone level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0005122I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff
• decreased circulating thyroxine level_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tg-cre)1Soff/0
  http://metadb.riken.jp/0005478I129P2OlaHsd129S7SvEvBrdC57BL6Gna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTgcre1Soff0Gna11tm1SoffGnaqtm2SoffTgTgcre1Soff