Steven C. Pruitt, et.al., Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer., Stem cells, 2007, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/17717065

Steven C. Pruitt, et.al., Reduced Mcm2 expression results in severe stem/progenitor cell deficiency and cancer., Stem cells, 2007, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3818719

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• muscle weakness_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0000747I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• increased thymoma incidence_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0014127I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal cell cycle_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0003077I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• hunched posture_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0001505I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• hypoactivity_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0001402I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal postnatal subventricular zone morphology_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0004275I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal cell nucleus morphology_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0003111I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal coat/hair pigmentation_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0002075I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• decreased total body fat amount_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0010025I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal small intestinal villus morphology_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0008108I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• sparse hair_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0000416I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal small intestine crypts of Lieberkuhn morphology_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0004841I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• premature death_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0002083I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• enlarged spleen_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0000691I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• colon polyps_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0003269I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal erythrocyte morphology_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0002447I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• intestine polyps_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0008011I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr
• abnormal breathing pattern_Mcm2<tm1(cre/ERT2)Scpr>/Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/0001951I129S6SvEvTacMcm2tm1creERT2ScprMcm2tm1creERT2ScprMcm2tm1creERT2Scpr

class

http://purl.org/net/cito/citesAsAuthority

• Mcm2<tm1(cre/ERT2)Scpr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3818719