Ping. Xie, et.al., Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs., Immunity, 2007, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17723217

Ping. Xie, et.al., Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs., Immunity, 2007, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Traf3<tm1Bshp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3722126

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immune system physiology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0001790I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased marginal zone B cell number_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008181I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgG2a level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008500I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• decreased physiological sensitivity to xenobiotic_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008874I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased B cell number_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0005014I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal lymph node B cell domain morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002344I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• enlarged spleen_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0000691I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal leukocyte morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008246I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgM level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002494I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• decreased T cell number_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0005018I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased spleen white pulp amount_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008478I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal immune system organ morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002722I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased anti-double stranded DNA antibody level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0004762I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgG level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002493I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal adaptive immunity_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002420I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased transitional stage B cell number_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008189I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgG3 level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008502I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal liver morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0000598I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• decreased B cell apoptosis_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008783I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased follicular B cell number_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008173I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• autoimmune response_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0001844I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgA level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002495I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal kidney morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002135I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• increased IgG2b level_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008501I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• enlarged lymph nodes_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0000702I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn
• abnormal spleen germinal center morphology_Traf3<tm1Bshp>/Traf3<tm1Bshp>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002359I129P2OlaHsd129S6SvEvTacC57BL6SJLTraf3tm1BshpTraf3tm1BshpCd19tm1creCgnCd19Cd19Traf3tm1BshpCd19tm1creCgn

class

http://purl.org/net/cito/citesAsAuthority

• Traf3<tm1Bshp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3722126