Alice E. Zemljic-Harpf, et.al., Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy., Molecular and cellular biology, 2007, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17785437

Alice E. Zemljic-Harpf, et.al., Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy., Molecular and cellular biology, 2007, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Vcl<tm1Ross>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769142

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased cardiac muscle contractility_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0005140I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• congestive heart failure_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0006138I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal intercalated disc morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0006267I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal impulse conducting system conduction_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0003137I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• irregular heartbeat_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0001636I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• cardiac fibrosis_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0003141I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal myocardial fiber morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0000278I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• heart block_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0010559I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• dilated heart left ventricle_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0002753I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• dilated cardiomyopathy_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0002795I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal cardiac muscle relaxation_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0004084I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal cardiovascular system morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0002127I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• premature death_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0002083I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• abnormal cardiovascular system physiology_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0001544I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• increased heart weight_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0002833I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• ventricular tachycardia_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0008950I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross
• cardiac hypertrophy_Myl2<tm1(cre)Krc>/Myl2<+>,Vcl<tm1Ross>/Vcl<tm1Ross>
  http://metadb.riken.jp/0001625I129S4SvJaeBlackSwissC57BL6SJLMyl2tm1creKrcMyl2Vcltm1RossVcltm1RossMyl2Myl2tm1creKrcVcltm1Ross

class

http://purl.org/net/cito/citesAsAuthority

• Vcl<tm1Ross>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769142