Irene. Siegl-Cachedenier, et.al., Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres., Genes & development, 2007, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/17785530

Irene. Siegl-Cachedenier, et.al., Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres., Genes & development, 2007, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• chromosomal instability_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008866I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• chromosomal instability_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008866I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• increased enterocyte apoptosis_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008885I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal enterocyte proliferation_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008883I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• premature death_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0002083I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• increased lymphoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0012431I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• increased lymphoma incidence_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0012431I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• increased carcinoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0002038I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• abnormal telomere length_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0003155I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal DNA repair_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008058I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal DNA repair_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008058I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• abnormal intestine morphology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0000477I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• abnormal cell physiology_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0005621I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• abnormal telomere length_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0003155I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• increased enterocyte apoptosis_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0008885I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• abnormal intestine morphology_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0000477I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• increased carcinoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0002038I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• increased sarcoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0002032I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• abnormal cell physiology_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0005621I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• premature death_Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0002083I129SvC57BL6C57BL6JSJLTerctm1RdpTerctm1RdpTerctm1Rdp
• increased lymphoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0012431I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk
• abnormal cell physiology_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0005621I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• chromosomal instability_Pms2<tm1Lisk>/Pms2<tm1Lisk>
  http://metadb.riken.jp/0008866I129S2SvPasPms2tm1LiskPms2tm1LiskPms2tm1Lisk
• increased sarcoma incidence_Pms2<tm1Lisk>/Pms2<tm1Lisk>,Terc<tm1Rdp>/Terc<tm1Rdp>
  http://metadb.riken.jp/0002032I129Sv129S2SvPasC57BL6C57BL6JSJLPms2tm1LiskPms2tm1LiskTerctm1RdpTerctm1RdpTerctm1RdpPms2tm1Lisk