M V. Pletnikov, et.al., Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia., Molecular psychiatry, 2008, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/17848917

M V. Pletnikov, et.al., Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia., Molecular psychiatry, 2008, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-DISC1*)1001Plet
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838645

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal lateral ventricle morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0000823IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay
• increased aggression towards mice_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0001353IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay
• hyperactivity_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0001399IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay
• abnormal social/conspecific interaction_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0002557IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay
• abnormal neuron morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0002882IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay
• abnormal spatial reference memory_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-DISC1*)1001Plet/0
  http://metadb.riken.jp/0008414IC57BL6CBASJLTgCamk2atTA1Mmay0TgtetODISC11001Plet0TgtetODISC11001PletTgCamk2atTA1Mmay

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-DISC1*)1001Plet
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838645