Takashi. Matsuzaka, et.al., Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance., Nature medicine, 2007, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/17906635

Takashi. Matsuzaka, et.al., Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance., Nature medicine, 2007, 13

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased fatty acid oxidation_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0014172I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• embryonic lethality, incomplete penetrance_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0011102I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• abnormal lipid homeostasis_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0002118I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• decreased circulating insulin level_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0002727I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• improved glucose tolerance_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0005292I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• decreased circulating leptin level_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0005668I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• abnormal pancreatic islet morphology_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0005215I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• abnormal fatty acid level_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0005280I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• abnormal hepatocyte physiology_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0010080I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• abnormal liver morphology_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0000598I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• hepatic steatosis_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0002628I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• increased lean body mass_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0003960I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex
• increased insulin sensitivity_Elovl6<Gt(OST222498)Lex>/Elovl6<Gt(OST222498)Lex>
  http://metadb.riken.jp/0002891I129S5SvEvBrdC57BL6Elovl6GtOST222498LexElovl6GtOST222498LexElovl6GtOST222498Lex